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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Life events and acute cardiovascular reactions to mental stress: a cohort study.
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Life events and acute cardiovascular reactions to mental stress: a cohort study.

机译：生活事件和对精神压力的急性心血管反应：一项队列研究。

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OBJECTIVE: This study addressed the issue of whether frequent exposure to life events is associated with aggravation or blunting of cardiovascular reactions to acute mental stress. METHODS: In a substantial cohort of 585 healthy young adults, systolic and diastolic blood pressure and pulse rate were recorded at rest and in response to a mental arithmetic stress task. Participants indicated, from a list of 50 events, those they had experienced in the last year. RESULTS: There was an overall association between life events and blunted cardiovascular reactivity that was driven by variations in the frequency of exposure to desirable events. The total number of events and the number of personal events were negatively associated with systolic blood pressure and pulse rate reactions to acute stress, whereas the number of work-related events was negatively associated with diastolic blood pressure and pulse rate reactivity. The negative association between total events and systolic blood pressure reactivity wasstronger for women than men, whereas men exposed to frequent undesirable events showed enhanced diastolic blood pressure reactivity. The blunting of pulse rate reactivity associated with frequent personal life events was evident particularly for those who had a relatively large number of close friends. CONCLUSION: The nature and extent of the association between life events exposure and stress reactivity in young adults depends on the valence of the events together with the sex of the individual and their social network size.
机译：目的：本研究解决了频繁暴露于生活事件是否与急性精神压力的心血管反应加重或减弱相关的问题。方法：在585名健康的成年人中，记录了静息时和对心理算术压力任务的反应时的收缩压和舒张压以及脉搏率。参与者从50个事件的列表中指出了他们去年的经历。结果：生活事件与心血管反应迟钝之间存在总体联系，这是由暴露于期望事件的频率变化所驱动的。事件的总数和个人事件的数量与收缩压和对急性应激的脉搏率反应呈负相关，而与工作相关的事件数与舒张压和脉搏率反应性呈负相关。女性的总事件与收缩压反应性之间的负相关性比男性强，而经常发生不良事件的男性则显示出舒张压反应性增强。与频繁的个人生活事件相关的脉搏反应性的减弱尤其明显，对于那些拥有大量密友的人而言。结论：年轻人的生活事件暴露与压力反应之间的关联的性质和程度取决于事件的发生率，个体性别及其社交网络规模。

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