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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Socioeconomic status, race, and diurnal cortisol decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.
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Socioeconomic status, race, and diurnal cortisol decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.

机译：年轻人冠状动脉风险发展中的社会经济地位，种族和昼夜皮质醇下降（CARDIA）研究。

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OBJECTIVES: The objectives of this study were to assess whether socioeconomic status (SES) is associated with dysregulation of the cortisol diurnal rhythm and whether this association is independent of race and occurs equally in whites and blacks; and to determine if an association between SES and cortisol can be explained (is mediated) by behavioral, social, and emotional differences across the SES gradient. METHODS: Seven hundred eighty-one subjects from a multisite sample representing both whites and blacks provided six saliva cortisol samples over the course of the day: at awakening, 45 minutes, 2.5 hours, 8 hours, and 12 hours after awakening, and at bedtime. RESULTS: Both lower SES (education and income) and being black were associated with higher evening levels of cortisol. These relationships were independent of one another and SES associations with cortisol were similar across racial categories. The evidence was consistent with poorer health practices (primarily smoking), higher levels of depressive symptoms, poorer social networks and supports, and feelings of helplessness (low mastery) mediating the link between SES and cortisol. However, we found no evidence for psychosocial or behavioral mediation of the association between race and cortisol response. CONCLUSIONS: Lower SES was associated in a graded fashion with flatter diurnal rhythms as a result of less of a decline during the evening. This association occurred independent of race and the data were consistent with mediation by health practices, emotional and social factors. Blacks also showed a flatter rhythm at the end of the day. This association was independent of SES and could not be explained by behavioral, social, or emotional mediators.
机译：目的：本研究的目的是评估社会经济状况（SES）是否与皮质醇昼夜节律失调有关，以及这种关系是否独立于种族，并且在白人和黑人中均相同。并确定是否可以通过SES梯度上的行为，社交和情感差异来解释（介导）SES和皮质醇之间的关联。方法：从多地点样本中代表白人和黑人的781名受试者在一天的过程中提供了六个唾液皮质醇样本：清醒，醒后45分钟，2.5小时，8小时和12小时以及就寝时间。结果：较低的SES（教育和收入）和黑色都与夜间皮质醇水平升高有关。这些关系彼此独立，并且在不同种族类别中，SES与皮质醇的关联相似。这些证据与较差的健康习惯（主要是吸烟），抑郁症状水平较高，社交网络和支持较差以及在SES和皮质醇之间介导的无助感（精通程度低）相一致。但是，我们没有发现种族和皮质醇反应之间相关性的社会心理或行为调解证据。结论：较低的SES以分级的方式与较平坦的昼夜节律相关，这是由于夜间下降较少。这种关联独立于种族而发生，并且数据与健康习惯，情感和社会因素的调解一致。黑人在一天结束时也表现出较平坦的节奏。这种关联独立于SES，不能由行为，社会或情感中介来解释。

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