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Core mental state in irritable bowel syndrome.

机译:肠易激综合症的核心精神状态。

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OBJECTIVE: Psychiatric illness is higher among patients with irritable bowel syndrome (IBS) who seek medical care; however, a specific psychopathology that differentiates patients with IBS from patients with other organic gastrointestinal disorders has not been found. In the study described here, we investigated the predominant psychiatric symptoms in women with IBS. METHODS: The criteria of Manning et al., as modified by Thompson et al., were used to make the diagnoses of IBS. Psychiatric assessment was performed by using a structured interview in 64 women, aged 20 to 70 years, 36 with IBS and 28 with chronic cholelithiasis. Diagnosis of chronic cholelithiasis was made by histopathological examination. The final diagnoses were confirmed by interview after 1 year. The diagnostic system based on the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) was used to make the current diagnoses. The Present State Examination (PSE)-Index of Definition (ID) computer program (CATEGO) was used to define total psychopathology (total PSE score), current clinical severity (ID), and clusters of psychiatric symptoms. RESULTS: No difference in the specific DSM-IV diagnostic categories was found, but there were more total depressive disorders in the IBS group. The ID and total PSE score were high among patients with IBS. Multiple logistic regression analysis showed that duration of gastrointestinal pain, and the symptoms of general anxiety, and hypochondriasis significantly predicted a diagnosis of IBS. CONCLUSIONS: Female patients with IBS are categorized into the general DSM-IV category of depressive disorder, their current psychiatric severity is high compared with that of women with chronic cholelithiasis, and patients with IBS are characterized by the psychiatric syndromes of general anxiety and hypochondriasis. The implications of these findings and areas for future research are discussed.
机译:目的:肠易激综合症(IBS)患者中就医的精神疾病较高;然而,尚未发现将IBS患者与其他器质性胃肠疾病患者区分开的特定心理病理学。在本文所述的研究中,我们调查了IBS女性患者的主要精神症状。方法:采用汤普森(Thompson)等人修改的Manning等人的标准进行IBS的诊断。通过对64名年龄在20至70岁,36名患有IBS和28名患有慢性胆石症的女性进行结构化访谈,进行了精神病学评估。通过组织病理学检查诊断为慢性胆石症。一年后通过访谈确认了最终诊断。基于第四版《精神疾病诊断和统计手册》(DSM-IV)的诊断系统用于进行当前诊断。当前状态考试(PSE)-定义索引(ID)计算机程序(CATEGO)用于定义总体精神病理(总PSE评分),当前临床严重程度(ID)和精神病症状群。结果:在特定的DSM-IV诊断类别中没有发现差异,但IBS组的总抑郁症较多。 IBS患者的ID和PSE总得分较高。多元logistic回归分析表明,胃肠道疼痛的持续时间,全身性焦虑和软骨病的症状显着预测了IBS的诊断。结论:IBS女性患者被归类为抑郁症的一般DSM-IV类别,与慢性胆石症女性相比,其目前的精神病严重性高,IBS患者的特征在于全身性焦虑和软骨病的精神病综合症。讨论了这些发现和领域对未来研究的意义。

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