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Do men and women differ on measures of mental stress-induced ischemia?

机译:男性和女性在精神压力诱发的缺血性措施上是否有所不同?

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OBJECTIVE: To consider the effects of gender on ischemia in a larger sample, with broadly defined coronary artery disease (CAD). Mental stress has been shown to cause transient myocardial ischemia in a significant percentage of people with CAD. However, little is known about the effects of mental stress on ischemic processes in women. Most studies to date either had few women or required a positive exercise stress test. METHODS: Participants (61 women, 93 men; average age = 63 years) had documented CAD (positive stress test, abnormal catheterization even with minimal disease, or previous myocardial infarction). They underwent mental stress testing and radionuclide perfusion imaging (stress/ rest). Cardiac function data were collected and stress was compared with baseline. The data were then submitted to a series of analyses of variance. RESULTS: A total of 50 (32%) participants exhibited reversible ischemia post psychological stress. This reflects a relative rate of 33% (n = 31 of 93) for men and 31% (n = 19 of 61) for women. No difference between men and women were observed on any measure of hemodynamic functioning (blood pressure, heart rate, or cardiac perfusion). CONCLUSIONS: Results of this study showed no significant differences between men and women on measures of hemodynamic functioning or cardiac perfusion.
机译:目的:考虑性别对较大样本,定义明确的冠状动脉疾病(CAD)的局部缺血的影响。研究表明,很大一部分CAD患者中,精神压力会导致短暂性心肌缺血。但是,关于精神压力对女性缺血过程的影响知之甚少。迄今为止,大多数研究要么只有很少的女性,要么需要进行积极的运动压力测试。方法:参与者(61名女性,93名男性;平均年龄= 63岁)已经记录了CAD(正向压力测试,导管插管异常,即使疾病极少,或先前有心肌梗塞)。他们进行了心理压力测试和放射性核素灌注成像(压力/休息)。收集心脏功能数据,并将压力与基线进行比较。然后将数据提交给一系列方差分析。结果:共有50名(32%)参与者在心理压力后表现出可逆性缺血。这反映出男性的相对比率为33%(n = 93,共31),女性的相对比率为31%(n = 61,共19)。在任何血液动力学功能指标(血压,心率或心脏灌注)上均未观察到男女之间的差异。结论:这项研究的结果表明,男女在血流动力学功能或心脏灌注测量方面无显着差异。

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