首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Predictors of irritable bowel-type symptoms and healthcare-seeking behavior among adults with celiac disease.
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Predictors of irritable bowel-type symptoms and healthcare-seeking behavior among adults with celiac disease.

机译:患有腹腔疾病的成年人肠易激型症状和寻求医疗保健行为的预测指标。

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OBJECTIVES: To assess the frequency of irritable bowel syndrome (IBS)-type symptoms and consecutive healthcare-seeking behavior, their impact on health-related quality of life (HRQOL), and their possible biopsychosocial determinants in adult patients with celiac disease (CD). METHODS: A total of 1000 adult patients with CD from the German Celiac Society completed a medical (including bowel) and a sociodemographic questionnaire, the Short Form Health Survey (SF-36), and the Hospital Anxiety and Depression Scale through a postal survey. RESULTS: Of 412 respondents with reported biopsy-proven diagnosis with major adherence to a gluten-free diet (GFD) for > or =1 year, 96 (23.3%) patients fulfilled the modified Rome I criteria for IBS. Of these 96 patients, 76 (79.2%) sought help (medical and/or nonmedical) due to bowel symptoms (referred to as patients with IBS). IBS-type symptoms had a significant negative impact on the physical summary score of the SF-36 (p = .05). Mental disorder (OR = 2.29; beta = 0.83; p = .006); female sex (OR = 2.34; beta = 0.85; p = .03), and occasional nonadherence to GFD (OR = 1.74; beta = 0.56; p = .05) were risk factors for IBS-type symptoms. Active medical comorbidities predicted IBS-patient status (OR = 0.40; beta = -0.92; p = .001). CONCLUSIONS: The data support the biopsychosocial model of IBS: IBS-type symptoms in adult patients with CD can be explained through an interaction of clinical and sociopsychological mechanisms.
机译:目的:评估肠易激综合征(IBS)型症状和连续寻求医疗行为的频率,其对健康相关生活质量的影响(HRQOL)以及成人腹腔疾病(CD)患者可能的生物心理社会决定因素。方法:总共1000名来自德国腹腔疾病学会的成年CD患者通过邮政调查完成了医学(包括肠道)和社会人口统计学问卷,简明健康调查(SF-36)以及医院焦虑和抑郁量表。结果:在412名经活检证实诊断且主要坚持使用无麸质饮食(GFD)≥1年的受访者中,有96名(23.3%)患者符合IBS修改后的Rome I标准。在这96名患者中,有76名(79.2%)因肠症状而寻求帮助(医疗和/或非医疗)(称为IBS患者)。 IBS型症状对SF-36的身体综合评分有明显的负面影响(p = 0.05)。精神障碍(OR = 2.29; beta = 0.83; p = .006);女性(OR = 2.34; beta = 0.85; p = .03),偶尔不遵守GFD(OR = 1.74; beta = 0.56; p = 0.05)是IBS型症状的危险因素。活动性合并症可预测IBS患者的病情(OR = 0.40;β= -0.92; p = 0.001)。结论:该数据支持IBS的生物心理社会模型:成年CD患者的IBS型症状可以通过临床和社会心理学机制的相互作用来解释。

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