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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Behavioral mediation of the relationship between psychosocial factors and HIV disease progression.
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Behavioral mediation of the relationship between psychosocial factors and HIV disease progression.

机译：心理社会因素与HIV疾病进展之间关系的行为中介。

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摘要

The psychological and physical demands of coping with medication side effects and comorbid illnesses can be overwhelming and may influence behaviors, such as medication adherence, substance use, sexual risk behavior, and exercise that, in turn, affect health outcomes. Cross-sectional and prospective studies among diverse populations of persons living with HIV suggest that these behavioral mechanisms may be associated with HIV disease progression. The motivation to change behavior is often highest in the immediate aftermath of a stressor. However, over time the motivation to continue a particular behavior change is often challenged by habits, environmental influences, and psychosocial factors. Furthermore, a number of studies suggest that behavioral mechanisms may mediate the relationship between psychosocial variables (e.g., stress, depression, coping, and social support) and disease progression in HIV. Thus, developing clinical interventions that address these psychosocial factors and enhance protective health behaviors and reduce behaviors that convey risk to health are likely to lessen overall morbidity and mortality among patients living with HIV/AIDS.
机译：应对药物副作用和合并症的心理和生理需求可能是压倒性的，并且可能影响行为，例如药物依从性，药物使用，性危险行为以及锻炼，进而影响健康结果。对艾滋病毒感染者的不同人群的横断面和前瞻性研究表明，这些行为机制可能与艾滋病毒的病情发展有关。改变压力的动机通常是在压力源后立即产生的。然而，随着时间的流逝，继续进行特定行为改变的动力常常受到习惯，环境影响和社会心理因素的挑战。此外，许多研究表明，行为机制可能介导心理社会变量（例如压力，抑郁，应对和社会支持）与艾滋病病毒感染之间的关系。因此，开发针对这些心理社会因素并增强保护性健康行为并减少可能危害健康的行为的临床干预措施可能会降低艾滋病毒/艾滋病患者的总体发病率和死亡率。

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