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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Comorbid depression, chronic pain, and disability in primary care.
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Comorbid depression, chronic pain, and disability in primary care.

机译：合并抑郁症，慢性疼痛和初级保健中的残疾。

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OBJECTIVES: The objectives of this study were to provide estimates of the prevalence and strength of association between major depression and chronic pain in a primary care population and to examine the clinical burden associated with the two conditions, singly and together. METHODS: A random sample of Kaiser Permanente patients who visited a primary care clinic was mailed a questionnaire assessing major depressive disorder (MDD), chronic pain, pain-related disability, somatic symptom severity, panic disorder, other anxiety, probable alcohol abuse, and health-related quality of life (HRQL). Instruments included the Patient Health Questionnaire, SF-8, and Graded Chronic Pain Questionnaire. A total of 5808 patients responded (54% of those eligible to participate). RESULTS: Among those with MDD, a significantly higher proportion reported chronic (i.e., nondisabling or disabling) pain than those without MDD (66% versus 43%, respectively). Disabling chronic pain was present in 41% of those with MDD versus 10% of those without MDD. Respondents with comorbid depression and disabling chronic pain had significantly poorer HRQL, greater somatic symptom severity, and higher prevalence of panic disorder than other respondents. The prevalence of probable alcohol abuse/dependence was significantly higher among persons with MDD compared with individuals without MDD regardless of pain or disability level. Compared with participants without MDD, the prevalence of other anxiety among those with MDD was more than sixfold greater regardless of pain or disability level. CONCLUSIONS: Chronic pain is common among those with MDD. Comorbid MDD and disabling chronic pain are associated with greater clinical burden than MDD alone.
机译：目的：本研究的目的是提供初级保健人群中主要抑郁症和慢性疼痛之间的关联程度和强度，并单独和一起研究与这两种情况相关的临床负担。方法：随机向就诊于初级保健诊所的Kaiser Permanente患者样本发送问卷，以评估主要抑郁症（MDD），慢性疼痛，疼痛相关的残疾，躯体症状严重程度，恐慌症，其他焦虑症，可能的酒精滥用和健康相关的生活质量（HRQL）。仪器包括《患者健康调查表》，《 SF-8》和《分级慢性疼痛调查表》。共有5808名患者做出了反应（占符合条件的患者的54％）。结果：在患有MDD的患者中，慢性疼痛（即非致残或致残）的比例显着高于没有MDD的患者（分别为66％和43％）。有MDD的患者中有41％的人患有慢性疼痛，而没有MDD的患者中有10％。与其他受访者相比，合并抑郁症和慢性疼痛致残的受访者HRQL明显更差，躯体症状严重程度更高，并且恐慌症的患病率更高。与没有MDD的患者相比，MDD的患者中可能的酒精滥用/依赖性患病率要高得多，而无论疼痛或残障程度如何。与没有MDD的参与者相比，无论疼痛或残疾程度如何，患有MDD的参与者中其他焦虑的患病率高出六倍。结论：慢性疼痛在MDD患者中很常见。与仅MDD相比，MDD合并症和致残性慢性疼痛与更大的临床负担相关。

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