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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Joint effect of depression and chronic conditions on disability: results from a population-based study.
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Joint effect of depression and chronic conditions on disability: results from a population-based study.

机译：抑郁症和慢性疾病对残疾的共同影响：一项基于人群的研究结果。

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OBJECTIVES: To estimate and compare the prevalence of functional disability in individuals with both chronic medical conditions and comorbid major depression and individuals with either chronic medical conditions or major depression alone and to determine the joint effect of depression and chronic conditions on functional disability. Evidence exists that major depression interacts with physical illness to amplify the functional disability associated with many medical conditions. METHODS: We used data from the Canadian Community and Health Survey Cycle 2.1 (n = 46,262), a nationally representative survey conducted in 2003 by Statistics Canada. Depression, chronic conditions, and functional disability were assessed by personal/telephone interview. RESULTS: Prevalence of functional disability was higher in subjects with chronic conditions and comorbid major depression (46.3%) than in individuals with either chronic conditions (20.9%) or major depression (27.8%) alone. With no chronic conditions and no major depression as reference and after adjusting for relevant covariates, the odds ratio of functional disability was 2.49 (95% confidence interval (CI), 1.91-3.26) for major depression, 2.12 (95% CI, 1.93-2.32) for chronic conditions, and 6.34 (95% CI, 5.35-7.51) for chronic conditions and comorbid major depression. CONCLUSIONS: The results suggest that there is a joint effect of depression and chronic conditions on functional disability. Research and social policies should focus on the treatment of depression in chronic conditions.
机译：目的：评估和比较患有慢性医学疾病和合并症的重度抑郁症患者以及患有慢性医学疾病或仅患有重度抑郁症的患者的功能障碍患病率，并确定抑郁症和慢性疾病对功能障碍的联合影响。有证据表明，重度抑郁症与身体疾病相互作用，加剧了与许多医疗状况相关的功能障碍。方法：我们使用了来自加拿大社区和健康调查周期2.1（n = 46,262）的数据，该周期是加拿大统计局于2003年进行的全国代表调查。通过个人/电话访谈来评估抑郁症，慢性病和功能障碍。结果：患有慢性疾病和合并严重抑郁的受试者的功能障碍患病率高于单独患有慢性疾病（20.9％）或患有严重抑郁的个体（27.8％）。在没有慢性病且没有严重抑郁的情况下，经过相关协变量调整后，严重抑郁的功能障碍的优势比为2.49（95％置信区间（CI），1.91-3.26），2.12（95％CI，1.93-慢性疾病的患者评分为2.32（95％CI，5.35-7.51）（慢性疾病和合并性重度抑郁症）。结论：结果表明抑郁症和慢性疾病对功能障碍有联合作用。研究和社会政策应侧重于治疗慢性病中的抑郁症。

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