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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Higher prevalence of depressive symptoms in middle-aged men with low serum cholesterol levels.
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Higher prevalence of depressive symptoms in middle-aged men with low serum cholesterol levels.

机译：血清胆固醇水平低的中年男性抑郁症状的患病率较高。

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OBJECTIVE: Investigators from several studies have reported a positive relationship between low cholesterol levels and death due to violent causes (eg, suicide and accidents), possibly mediated by depressive symptoms, aggression or hostility, or impulsivity. We set out to establish whether middle-aged men with chronically low cholesterol levels (< or =4.5 mmol/liter) have a higher risk of having depressive symptoms, according to scores on the Beck Depression Inventory, compared with a reference group of men with cholesterol levels between 6 and 7 mmol/liter. A similar comparison was also made for measures of anger, hostility, and impulsivity. METHODS: Cholesterol measurements were obtained as part of a population-based cholesterol screening study in 1990-1991. These levels were remeasured in 1993-1994. Only those whose cholesterol level remained in the same range were included in the study. Depressive symptoms were assessed by using the Beck Depression Inventory; anger, by questionnaires based on the Spielberger Anger Expression Scale and State-Trait Anger Scale; hostility, by the Buss-Durkee Hostility Inventory; and impulsivity, by the Eysenck and Eysenck Impulsivity Questionnaire. RESULTS: Men with chronically low cholesterol levels showed a consistently higher risk of having depressive symptoms (Beck Depression Inventory score > or =15 or > or =17) than the reference group, even after adjusting for age, energy intake, alcohol use, and presence of chronic diseases. No differences in anger, hostility, and impulsivity were observed between the two groups. CONCLUSIONS: Men with a lower cholesterol level (< or =4.5 mmol/liter) have a higher prevalence of depressive symptoms than those with a cholesterol level between 6 and 7 mmol/liter. These data may be important in the ongoing debate on the putative association between low cholesterol levels and violent death.
机译：目的：来自几项研究的研究人员报告说，低胆固醇水平与暴力原因（例如自杀和事故）导致的死亡之间存在正相关关系，暴力原因可能是抑郁症状，攻击性或敌意或冲动性介导的。根据Beck抑郁量表上的得分，我们确定了长期处于低胆固醇水平（<或= 4.5 mmol / L）的中年男性是否具有较高的抑郁症状风险，而该组男性则低于胆固醇水平在6至7 mmol / L之间。对于愤怒，敌对和冲动的测量方法也进行了类似的比较。方法：在1990-1991年进行的一项基于人群的胆固醇筛选研究中，获得了胆固醇测量值。这些水平在1993-1994年进行了重新测量。本研究仅包括胆固醇水平保持在相同范围内的那些。使用贝克抑郁量表评估抑郁症状。通过基于斯皮尔伯格愤怒表达量表和状态特质愤怒量表的问卷进行愤怒;敌意，由Buss-Durkee敌意量表提供;和艾森克和艾森克冲动问卷。结果：即使调整了年龄，能量摄入，酒精摄入和酒精摄入量，长期处于低胆固醇水平的男性也显示出比对照组有更高的抑郁症状风险（贝克抑郁量表得分≥15或≥17）。存在慢性疾病。两组之间在愤怒，敌意和冲动方面没有差异。结论：胆固醇水平较低（<或= 4.5 mmol / L）的男性比胆固醇水平在6至7 mmol / L的男性更容易出现抑郁症状。在正在进行的有关低胆固醇水平与暴力死亡之间的可能联系的辩论中，这些数据可能很重要。

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