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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Lack of Social Support in the Etiology and the Prognosis of Coronary Heart Disease: A Systematic Review and Meta-Analysis
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Lack of Social Support in the Etiology and the Prognosis of Coronary Heart Disease: A Systematic Review and Meta-Analysis

机译：病因和冠心病预后缺乏社会支持：系统评价和荟萃分析

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Objective: To conduct a systematic review and meta-analysis on the relevance of low social support for the development and course of coronary heart disease (CHD). Methods: Three electronic databases were searched (MEDLINE, PsycINFO/PSYNDEX, and Web of Science 2007/03). More than 1700 papers were screened in a first step. We included prospective studies assessing the impact of social support in either an initially healthy study population (etiologic studies) or in a study population with preexisting CHD (prognostic studies). Outcomes: Myocardial infarction in etiologic studies; cardiovascular mortality and all-cause mortality in prognostic studies. Effects were reported as relative risk (RR) or hazard ratio (HR). Results: There is some evidence for an impact of low functional social support on the prevalence of CHD in etiologic studies (RR, range, 1.00-2.23). In contrast, there is no evidence of an impact of low structural social support on the prevalence of myocardial infarction in healthy populations (RR, range, 1.01-1.2). In prognostic studies, results consistently show that low functional support negatively affects cardiac and all-cause mortality (pooled RR, range, 1.59-1.71). These results were also confirmed in analyses adjusted for other risk factors for disease progression (pooled HR, 1.59). It remains unclear whether low structural social support increases mortality in patients with CHD (pooled RR, between 1.56; pooled HR, 1.12, NS). Conclusions: Because the perception of social support seems important for CHD prognosis, monitoring of functional social support is indicated in patients with CHD, and interventions to increase the perception of positive social resources are warranted.
机译：目的：对低社会支持与冠心病（CHD）的发展和进程的相关性进行系统的回顾和荟萃分析。方法：搜索了三个电子数据库（MEDLINE，PsycINFO / PSYNDEX和Web of Science 2007/03）。第一步筛选了1700多篇论文。我们纳入了前瞻性研究，以评估社会支持对最初健康的研究人群（病因学研究）或预先患有冠心病的研究人群（预后研究）的影响。结果：病因学研究中的心肌梗塞;心血管疾病死亡率和全因死亡率在预后研究中。效果报告为相对风险（RR）或危险比（HR）。结果：在病因学研究中，有一些证据表明功能低下的社会支持对冠心病的患病率有影响（RR，范围1.00-2.23）。相反，没有证据表明低结构的社会支持对健康人群的心肌梗死患病率有影响（RR，范围1.01-1.2）。在预后研究中，结果始终显示低功能支持会对心脏和全因死亡率产生负面影响（合并RR，范围1.59-1.71）。在针对疾病进展的其他风险因素进行调整的分析中也证实了这些结果（合并HR，1.59）。尚不清楚低结构性社会支持是否会增加冠心病患者的死亡率（合并RR为1.56;合并HR为1.12，NS）。结论：由于社会支持感对于冠心病的预后似乎很重要，因此应监测冠心病患者的功能性社会支持，并应采取干预措施以增加对积极社会资源的感性。

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