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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Association of baseline anxiety with depression persistence at 6 months in patients with acute cardiac illness.
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Association of baseline anxiety with depression persistence at 6 months in patients with acute cardiac illness.

机译：患有急性心脏病的患者在6个月时基线焦虑与抑郁持续存在相关性。

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OBJECTIVE: To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization. METHODS: Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhythmia and who were enrolled in a randomized trial of collaborative care depression management. Subjects' demographic, medical, and psychiatric information at baseline was compiled. Measures of health-related quality of life, cardiac symptoms, and psychiatric symptoms, including the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A) for anxiety, were obtained at baseline and serially during a 6-month follow-up period. The association between baseline HADS-A score and depression persistence (<50% reduction in depressive symptoms on the Patient Health Questionnaire-9) at 6 months was assessed by multivariate logistic regression accounting for the effects of multiple relevant medical and psychological covariates. The association between baseline HADS-A score and improvement in depressive symptoms (Patient Health Questionnaire-9) from baseline at 6 months was assessed by linear regression accounting for the same covariates. RESULTS: Baseline HADS-A score was independently associated with depression persistence at 6 months (odds ratio = 1.11, 95% confidence interval = 1.01-1.22, p = .03). Likewise, higher baseline HADS-A score was associated with less improvement in depressive symptoms at 6 months (beta = -0.34, p = .01). CONCLUSIONS: Among a cohort of depressed cardiac patients, higher baseline anxiety score was linked with lesser improvement in depressive symptoms and increased likelihood of depression persistence at 6 months, independent of multiple relevant covariates. Trial Registration: clinicaltrials.gov Identifier: NCT00847132.
机译：目的：评估心脏住院后6个月基线焦虑与抑郁持续性和抑郁症状变化之间的关系。方法：分析了137例因急性冠脉综合征，代偿性心力衰竭或心律失常而在住院心脏科住院的抑郁症患者的数据，这些患者参加了协作治疗抑郁症管理的随机试验。汇总了受试者在基线时的人口统计学，医学和精神病学信息。在基线和连续6个月的随访期间，获得了与健康相关的生活质量，心脏症状和精神症状的量度，包括焦虑症的医院焦虑和抑郁量表焦虑量表（HADS-A）。通过多元logistic回归评估了HADS-A基线评分与抑郁持续性（患者健康问卷9的抑郁症状降低<50％）之间的相关性，并考虑了多个相关医学和心理协变量的影响。基线HADS-A评分与6个月基线时抑郁症状改善（患者健康问卷9）之间的相关性通过考虑相同协变量的线性回归进行评估。结果：基线HADS-A评分与6个月时的抑郁持久性独立相关（赔率= 1.11，95％置信区间= 1.01-1.22，p = .03）。同样，较高的基线HADS-A评分与6个月时抑郁症状的改善较少相关（β= -0.34，p = 0.01）。结论：在一组抑郁的心脏病患者中，较高的基线焦虑评分与抑郁症状的改善较少和6个月时抑郁持续存在的可能性增加有关，而与多个相关协变量无关。试用注册：clinicaltrials.gov标识符：NCT00847132。

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