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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Acculturative stress and inflammation among Chinese immigrant women
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Acculturative stress and inflammation among Chinese immigrant women

机译：中国移民妇女的适应性压力和炎症

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OBJECTIVE: Among Chinese immigrant populations, increasing duration of US residence is associated with elevated risk for various chronic diseases. Although life-style changes after migration have been extensively studied in immigrant populations, the psychosocial impact of acculturative stress on biological markers of health is less understood. Thus, the purpose of the present study is to examine associations between acculturative stress and inflammatory markers in a Chinese immigrant population. METHODS: Study participants (n = 407 foreign-born Chinese American women) completed questionnaires assessing levels of stress, including acculturative stress and positive and negative life events in the previous year. Participant height and weight were measured using standard protocols, and blood samples were drawn for assessment of circulating serum levels of C-reactive protein (CRP) and soluble tumor necrosis factor receptor 2 (sTNFR2). RESULTS: Higher levels of acculturative stress were significantly associated with higher levels of CRP (B = 0.07, 95% confidence interval = 0.01-0.13, p = .031) and sTNFR2 (B = 0.02, 95% confidence interval = 0.004-0.03, p = .012), adjusting for age and body mass index. The latter association was no longer statistically significant when overall acculturation (i.e., identification with American culture) was included in the model. Life events were not associated with CRP or sTNFR2. CONCLUSIONS: This is one of the first studies to demonstrate that acculturative stress is associated with inflammatory markers in a Chinese immigrant population. Replication in other immigrant samples is needed to fully establish the biological correlates and clinical consequences of acculturative stress.
机译：目的：在中国移民人口中，美国居留时间的增加与各种慢性疾病的风险增加有关。尽管已经在移民人口中广泛研究了移民后的生活方式变化，但是人们对适应性压力对健康的生物标志物的社会心理影响知之甚少。因此，本研究的目的是检验中国移民人群的适应性压力与炎症标志物之间的关系。方法：研究参与者（n = 407外国出生的美国华裔女性）完成了问卷，以评估压力水平，包括上一年的适应性压力以及正负生活事件。使用标准方案测量参与者的身高和体重，并抽取血样以评估循环血清C反应蛋白（CRP）和可溶性肿瘤坏死因子受体2（sTNFR2）的水平。结果：较高的适应压力与较高的CRP（B = 0.07，95％置信区间= 0.01-0.13，p = .031）和sTNFR2（B = 0.02，95％置信区间= 0.004-0.03， p = .012），调整了年龄和体重指数。当模型中包括整体适应性（即与美国文化的认同）时，后者的关联性就不再具有统计学意义。生活事件与CRP或sTNFR2无关。结论：这是首批证明文化适应压力与中国移民人口中的炎症标志物相关的研究之一。需要在其他移民样本中进行复制，以充分建立适应性应激的生物学相关性和临床后果。

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