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Screening for postnatal depression using the double-test strategy.

机译:使用双重测试策略筛查产后抑郁症。

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OBJECTIVE: Postnatal depression affects 10% to 15% of women after childbirth. Self-report rating instruments, such as the Edinburgh Postnatal Depression Scale (EPDS), have been developed and administered to postpartum women to facilitate early detection. Most postnatal depression screening scales, however, focus solely on depressive symptomatology. We hypothesized that applying two complementary rating scales of symptoms and functioning as a double test would significantly enhance the positive predictive value of screening. METHODS: A prospective cohort study was conducted at the postnatal clinic of a university teaching hospital. One hundred forty-five Chinese women completed the EPDS and 12-item General Health Questionnaire (GHQ) 6 weeks after delivery. They were then interviewed by a psychiatrist, who used the Structured Clinical Interview for third revised edition of the Diagnostic and Statistical Manual of Mental Disorders, nonpatient version (SCID-NP), to validate the diagnoses. RESULTS: The positive predictive value of the EPDS and GHQ, when administered independently, was 44% and 52%, respectively, at their respective optimal cutoff scores. When the EPDS-GHQ double test was administered, the positive predictive value was significantly increased to 78%. CONCLUSIONS: Simultaneous administration of the EPDS and GHQ can substantially improve identification of women with postnatal depression. This can potentially reduce unnecessary referrals to general practitioners and psychiatrists and may enhance the overall cost-effectiveness of population-wide screening.
机译:目的:产后抑郁症影响分娩后妇女的10%至15%。诸如爱丁堡产后抑郁量表(EPDS)之类的自我报告评估工具已经开发出来,并应用于产后妇女,以促进早期发现。然而,大多数产后抑郁筛查量表仅关注抑郁症状。我们假设应用两个互补的症状量表和双重检验功能将显着提高筛查的阳性预测价值。方法:在大学教学医院的产后诊所进行了一项前瞻性队列研究。 145名中国妇女在分娩后6周完成了EPDS和12个项目的一般健康问卷(GHQ)。然后,他们接受了一名心理医生的采访,该心理医生使用《结构性临床访谈》编制了《精神障碍诊断和统计手册》的第三修订版(非患者版本,SCID-NP),以验证诊断结果。结果:单独给药时,EPDS和GHQ的阳性预测值在各自的最佳临界评分下分别为44%和52%。进行EPDS-GHQ双重检测后,阳性预测值显着提高至78%。结论:同时使用EPDS和GHQ可以显着改善患有产后抑郁症的妇女的识别能力。这样可以减少不必要的转诊给全科医生和精神科医生的负担,并可以提高整个人群筛查的总体成本效益。

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