• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Somatic depression predicts mortality in chronic heart failure: Can this be explained by covarying symptoms of fatigue?
【24h】

Somatic depression predicts mortality in chronic heart failure: Can this be explained by covarying symptoms of fatigue?

机译：躯体性抑郁症可预测慢性心力衰竭的死亡率：这可以通过各种疲劳症状来解释吗？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: Somatic symptoms of depression predict mortality in chronic heart failure (CHF), but symptoms of fatigue that are common to both conditions may confound this association. We therefore examined the contribution of fatigue to the association between somatic depression and increased risk of mortality in patients with CHF. Methods: At baseline, 380 consecutive patients with CHF were assessed for symptoms of depression, exertion fatigue, and general fatigue. Demographic and clinical data were obtained from the patients' medical records or the treating cardiologist. The primary end point was mortality after a median follow-up of 2.3 years (range = 0.15-4.76 years). Results: At follow-up, 63 patients (16.6%) had died. Exertion fatigue (hazard ratio [HR] = 1.04, 95% confidence interval [CI] = 1.01-1.06, p = .003), not general fatigue, was associated with an increased risk of mortality in CHF. Multivariate Cox regression analysis revealed that somatic symptoms of depression (HR = 1.41, 95% CI = 1.05-1.88, p = .02) were independently associated with increased mortality risk and that this association could not be explained by exertion fatigue (HR = 1.02, 95% CI = 0.97-1.05, p = .31). Conclusions: The adverse effect of somatic depression on prognosis in CHF was not confounded by exertion fatigue. Behavioral interventions should focus not only on fatigue but also on other somatic manifestations of depression in patients with CHF. Abbreviations: CHF = chronic heart failureLVEF = left ventricular ejection fractionBDI = Beck Depression InventoryPCA = principal components analysis
机译：目的：抑郁症的躯体症状可预测慢性心力衰竭（CHF）的死亡率，但两种情况下常见的疲劳症状可能会混淆这种关联。因此，我们检查了疲劳对CHF患者躯体抑郁与死亡风险增加之间关系的影响。方法：在基线时，对380名连续的CHF患者进行了抑郁，劳累性疲劳和全身性疲劳的症状评估。人口统计学和临床​​数据来自患者的病历或主治心脏病专家。主要终点是中位随访时间2.3年（范围= 0.15-4.76年）后的死亡率。结果：随访时死亡63例（16.6％）。劳累疲劳（危险比[HR] = 1.04，95％置信区间[CI] = 1.01-1.06，p = 0.003），而不是一般的疲劳，与CHF的死亡风险增加相关。多元Cox回归分析显示，抑郁的躯体症状（HR = 1.41，95％CI = 1.05-1.88，p = .02）与死亡风险增加独立相关，并且这种关联不能由劳累疲劳解释（HR = 1.02） ，95％CI = 0.97-1.05，p = .31）。结论：躯体抑郁对CHF预后的不良影响与劳累乏力无关。行为干预措施不仅应关注疲劳，还应关注CHF患者抑郁症的其他躯体表现。缩写：CHF =慢性心力衰竭LVEF =左心室射血分数BDI =贝克抑郁量表PCA =主成分分析

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号