• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Psychosomatics >Depressive symptoms in pulmonary arterial hypertension: prevalence and association with functional status.
【24h】

Depressive symptoms in pulmonary arterial hypertension: prevalence and association with functional status.

机译：肺动脉高压的抑郁症状：患病率和与功能状态的关联。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: In patients with left-heart disease, depressive symptoms have a significant impact on functional status and quality of life. The prevalence of depressive symptoms, and their impact on patients with pulmonary arterial hypertension (PAH) is understudied. OBJECTIVE: The authors investigated the prevalence of depressive symptoms in PAH and their correlation with physical functioning. METHOD: Consecutive outpatients with PAH (idiopathic; or associated with scleroderma, congenital heart disease, or anorexiant use) seen in two university PAH clinics were screened. At two outpatient visits, 8 to 16 weeks apart, patients completed the PHQ-8, a well-validated instrument for grading severity of depressive symptoms; they were assessed for cardiac functional class (FC), and performed a 6-minute walk-distance test (6MWD). RESULTS: A group of 100 patients (88% women, 50% with idiopathic PAH) were enrolled. At baseline, 15% of subjects had symptoms suggestive of major depressive disorder; 40% had mild-to-moderate depressive symptoms; and 45% had no-to-minimal depressive symptoms. CONCLUSION: Depression is common in patients with PAH, with 55% demonstrating depressive symptoms. These results suggest that screening patients with PAH will identify a large proportion of patients who might benefit from depression therapy.
机译：背景：在患有左心疾病的患者中，抑郁症状对功能状态和生活质量有重大影响。抑郁症状的发生率及其对肺动脉高压（PAH）患者的影响尚未得到研究。目的：作者调查了PAH中抑郁症状的患病率及其与身体功能的相关性。方法：对在两个大学PAH诊所中发现的连续性PAH（特发性;或与硬皮病，先天性心脏病或厌食症相关的）门诊病人进行筛查。在两次相隔8至16周的门诊就诊时，患者完成了PHQ-8，PHQ-8是一种有效的抑郁症状严重程度分级工具。对他们的心脏功能等级（FC）进行了评估，并进行了6分钟的步行距离测试（6MWD）。结果：纳入一组100例患者（88％为女性，50％为特发性PAH）。基线时，有15％的受试者有暗示严重抑郁症的症状; 40％有轻度至中度的抑郁症状; 45％的人没有最低程度的抑郁症状。结论：PAH患者抑郁很常见，有55％的患者表现出抑郁症状。这些结果表明，筛查PAH的患者将确定可能从抑郁疗法中受益的大部分患者。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号