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Pre-existing major depression predicts in-hospital cardiac complications after acute myocardial infarction.

机译:先前存在的严重抑郁症可预测急性心肌梗塞后的院内心脏并发症。

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BACKGROUND: Depression (MDD) and anxiety have been associated with negative long-term outcomes among patients with acute myocardial infarction (MI). OBJECTIVE: The objective of the study was to determine whether MDD and anxiety preceding MI were associated with in-hospital post-MI cardiac complications. METHOD: Subjects (N=129) underwent psychiatric interviews within 72 hours of MI and were evaluated for five in-hospital cardiac complications (recurrent ischemia, ventricular arrhythmia, ventricular arrhythmia requiring intervention, congestive heart failure, and reinfarction). RESULTS: Current (pre-MI) MDD was a significant and independent predictor of all complications except recurrent ischemia on multivariate regression analysis. In contrast, pre-MI anxiety was not associated with complications. CONCLUSION: These findings underscore the importance of identifying and treating MDD in post-MI patients and those at risk for MI.
机译:背景:急性心肌梗死(MI)患者长期抑郁与抑郁(MDD)相关。目的:研究的目的是确定心肌梗死前的MDD和焦虑症是否与院内心梗后心脏并发症有关。方法:对象(N = 129)在MI的72小时内接受了精神病学采访,并评估了五种院内心脏并发症(反复缺血,室性心律不齐,需要干预的室性心律不齐,充血性心力衰竭和再梗塞)。结果:当前(MI前)MDD是所有并发症的重要且独立的预测因素,但基于多元回归分析的复发性缺血除外。相反,心肌梗死前的焦虑与并发症无关。结论:这些发现强调了在MI后患者和有MI风险的患者中鉴定和治疗MDD的重要性。

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