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首页> 外文期刊>Psychosomatics >A prospective examination of antidepressant use and its correlates in patients with acute coronary syndrome.
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A prospective examination of antidepressant use and its correlates in patients with acute coronary syndrome.

机译：急性冠脉综合征患者抗抑郁药的使用及其相关性的前瞻性检查。

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BACKGROUND: Depression has been implicated in the occurrence of recurrent coronary events and cardiac or all-cause mortality in acute coronary syndrome (ACS) patients. OBJECTIVE: The authors describe the frequency and type of antidepressant use and its correlates 18 months after ACS hospital discharge. METHOD: A sample of 661 ACS inpatients, recruited from three hospitals, completed a sociodemographic survey and the Hospital Anxiety and Depression Scale (HADS), and clinical data were extracted from charts. A mailed survey 9 months and 18 months post-discharge assessed self-reported antidepressant use, and the HADS was re-administered. RESULTS: Approximately 9% of participants reported antidepressant use both 9 and 18 months post-hospitalization, with 77% concordance in usage over time. Participants most frequently reported using selective serotonin reuptake inhibitors and least often tricyclics. Logistic regression revealed that antidepressant users were more likely to be anxious and have more comorbidity, and were less likely to work full-time, whereas number of medications, age, and marital status were not related. CONCLUSION: Patients with comorbid physical and mental conditions who are unemployed may be more likely to receive an antidepressant because of greater depression symptoms or greater exposure to healthcare providers, which increases the potential for symptom recognition and treatment.
机译：背景：抑郁症与急性冠状动脉综合征（ACS）患者的复发性冠脉事件和心脏或全因死亡率的发生有关。目的：作者描述了抗抑郁药的使用频率和类型及其与ACS出院18个月后的关系。方法：从三家医院招募的661名​​ACS住院患者样本中，完成了社会人口统计学调查和医院焦虑与抑郁量表（HADS），并从图表中提取了临床数据。出院后9个月和18个月的邮寄调查评估了自我报告的抗抑郁药的使用，并重新施用了HADS。结果：大约9％的参与者在住院后9个月和18个月都报告了抗抑郁药的使用，随着时间的推移，一致使用抗抑郁药的比例为77％。参加者最经常报告使用选择性5-羟色胺再摄取抑制剂，最不常见的是使用三环类药物。 Logistic回归显示，抗抑郁药使用者更容易焦虑和合并症，全日制工作的可能性较小，而药物的使用次数，年龄和婚姻状况则无关。结论：失业的患有身体和精神病合并症的患者可能更可能接受抗抑郁药，因为抑郁症的症状更大或与医疗保健提供者的接触更大，这增加了症状识别和治疗的可能性。

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