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首页> 外文期刊>Psychosomatics >Depression after diagnosis of advanced non-small cell lung cancer and survival: a pilot study.
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Depression after diagnosis of advanced non-small cell lung cancer and survival: a pilot study.

机译：诊断为晚期非小细胞肺癌的抑郁症和生存率：一项前瞻性研究。

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BACKGROUND: Major depressive disorder is estimated to occur in 10%-25% of people with cancer, and it has been inconsistently linked to increased mortality. OBJECTIVE: This pilot study investigates the association of depression and survival in advanced non-small cell lung cancer (NSCLC) patients. METHOD: Forty-three recently-diagnosed advanced NSCLC patients completed the Hospital Anxiety and Depression Scale and were followed prospectively. RESULTS: Patients with depression had poorer survival. Median survival was four times shorter than those without depression. Controlling for baseline performance status, depression predicted 6-month mortality, but was not significant for overall survival. CONCLUSION: Although depression after advanced-NSCLC diagnosis was associated with poorer survival at 6 months, this association was not present for overall survival; however, further research with larger samples should be pursued.
机译：背景：据估计，重度抑郁症发生在10％-25％的癌症患者中，并且与死亡率增加并不一致。目的：这项初步研究调查了晚期非小细胞肺癌（NSCLC）患者抑郁与生存的关系。方法：43例最近诊断为晚期NSCLC的患者完成了《医院焦虑和抑郁量表》，并进行了前瞻性随访。结果：抑郁症患者的生存期较差。中位生存期比没有抑郁症的生存期短四倍。控制基线表现状态，抑郁症可预测6个月的死亡率，但对总体生存率无显着影响。结论：尽管晚期非小细胞肺癌诊断后的抑郁症与6个月生存期较差有关，但总生存期并不存在这种关系。但是，应该对更大的样本进行进一步的研究。

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