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A systematic review of psychosocial factors affecting survival after bone marrow transplantation.

机译:对影响骨髓移植后生存的社会心理因素的系统评价。

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摘要

An electronic database search identified 15 studies of psychosocial factors affecting survival after bone marrow transplantation. The studies were assessed for methodological quality by two reviewers using the procedures of Bland and colleagues. Although some studies found that psychological variables affect survival after bone marrow transplantation, the reviewers' analysis of the methodologically sound studies suggested that survival after bone marrow transplantation is not substantively affected by depressed mood or other psychopathology in adults or by social support in adults or children. Longer survival may be related to lower anxious preoccupation, life ratings before and soon after transplant in adults. Overall, however, the literature is insufficiently developed to provide definitive evidence for a relationship between psychological variables and survival after bone marrow transplantation. Future primary studies in this area should be designed to maximize replicability and generalizability.
机译:电子数据库搜索确定了影响骨髓移植后生存的社会心理因素的15项研究。两名评价者使用Bland及其同事的程序对研究的方法学质量进行了评估。尽管一些研究发现心理变量会影响骨髓移植后的生存,但评论者对方法学研究的分析表明,成年人的情绪低落或其他心理病理学或成年人或儿童的社会支持对骨髓移植后的生存没有实质性影响。更长的生存期可能与成人移植前和移植后不久的焦虑情绪降低和寿命降低有关。但是,总的来说,文献还不足以为骨髓移植后心理变量与生存之间的关系提供明确的证据。该领域未来的初步研究应设计为最大程度地提高可复制性和通用性。

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