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首页> 外文期刊>Psychosomatics >Depression as a prognostic factor for breast cancer mortality.
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Depression as a prognostic factor for breast cancer mortality.

机译：抑郁是乳腺癌死亡率的预后因素。

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It is unclear if depression or depressive symptoms have an effect on mortality in breast cancer patients. In this population-based, nationwide, retrospective cohort study in Denmark, depression was defined as affective or anxiety disorders that necessitated psychiatric hospital admission. All the affective and anxiety disorders were divided and categorized into five ordinal diagnostic groups. Early-stage (N=10382) and late-stage (N=10211) breast cancer patients were analyzed separately with Cox's regression adjusted for well-documented somatic prognostic variables. The authors used survival analysis of data from three central registers and found that breast cancer patients with depression had a modestly but significantly higher risk of mortality depending on stage of breast cancer and time of depression. The same result was found after censoring unnatural causes of death such as accident, suicide, or homicide.
机译：目前尚不清楚抑郁或抑郁症状是否会影响乳腺癌患者的死亡率。在丹麦的这项基于人群的全国性回顾性队列研究中，抑郁症被定义为必须住院的精神病或焦虑症。将所有的情感和焦虑症分为五个顺序诊断组。早期（N = 10382）和晚期（N = 10211）乳腺癌患者分别进行了分析，并针对有据可查的躯体预后变量进行了Cox回归调整。作者对来自三个中央登记处的数据进行了生存分析，发现患有抑郁症的乳腺癌患者根据乳腺癌的分期和抑郁时间，有适度但明显更高的死亡率。审查了意外，自杀或杀人等非自然死亡原因后，发现了相同的结果。

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