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Biophysics of mitosis

机译：有丝分裂的生物物理学

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Mitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules (MTs) and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly and motility processes required to do this complex job with precision. Work from both the recent and the older literature is integrated into a description of relevant biological events and the experiments that probe their mechanisms. Theoretical work on specific subprocesses is also reviewed. Our goal is to provide a document that will expose biophysicists to the fascination of this quite amazing process and provide them with a good background from which they can pursue their own research interests in the subject.
机译：有丝分裂是真核细胞组织和分离其染色体以准备细胞分裂的过程。它是由主要由微管（MTs）及其相关蛋白组成的细胞机器完成的。本文从生物物理学的角度回顾了有丝分裂的文献，提请人们注意精确完成这项复杂工作所需的组装和运动过程。最新文献和较旧文献的工作都被整合到有关生物事件的描述和探索其机理的实验中。还审查了有关特定子过程的理论工作。我们的目标是提供一个文档，使生物物理学家对这个令人惊奇的过程感兴趣，并为他们提供一个良好的背景，使他们可以从事该主题的自身研究兴趣。

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