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Paraneoplastic limbic encephalitis.

机译:副肿瘤性边缘性脑炎。

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BACKGROUND: Paraneoplastic limbic encephalitis (PLE) is a syndrome characterized by the development of neuropsychiatric symptoms due to a misdirected tumor-activated antibody response that damages host neural tissue. Definitive treatment relies on the identification and ablation of the underlying tumor. Few publications describe the management of psychiatric symptoms associated with PLE. OBJECTIVE: Given the plethora of neuropsychiatric symptoms that may mimic primary psychiatric illness, and the possibility that PLE may herald a life-threatening malignancy, it is important that psychiatrists become familiar with this condition. METHOD: The authors review and discuss the consensus literature on the various aspects of PLE. DISCUSSION: In this review, authors summarize proposed mechanisms and treatments of PLE.
机译:背景:副肿瘤性边缘性脑炎(PLE)是一种综合征,其特征是由于错误激活的肿瘤激活抗体反应导致宿主神经组织受损,导致神经精神症状的发展。确定性治疗依赖于潜在肿瘤的识别和消融。很少有出版物描述与PLE相关的精神症状的管理。目的:鉴于可能模仿原发性精神疾病的多种神经精神症状,以及PLE可能预示着危及生命的恶性肿瘤,因此精神科医生必须熟悉这种情况,这一点很重要。方法:作者回顾并讨论了关于PLE各个方面的共识性文献。讨论:在这篇综述中,作者总结了PLE的拟议机制和治疗方法。

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