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Brain Perfusion SPECT Scans in a Rural Child and Adolescent Outpatient Clinic

机译:农村儿童和青少年门诊的脑灌注SPECT扫描

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Diagnostic and background data were gathered on eight children and adolescents (four girls; four boys; ages 4 through 16) referred for neuroimaging to a small psychiatric inpatient unit. Referral questions were related to refractoriness to treatment, and the possibility of brain trauma or neurodevelopmental problems. Five individuals had been diagnosed with fetal alcohol syndrome and all were evincing externalizing or poorly controlled deportment. The results of structural imaging (magnetic resonance imaging or MRI) suggested significant under-development or atrophy for three of the participants. Functional imaging (single photon emission computed tomography or SPECT) however indicated left hemisphere hypoperfusion for all referred individuals. The location of hypoperfusion is consistent with manifestations of poor impulse control, the common behavioral element among the patients. The findings suggest that SPECT may be more sensitive to subtle brain abnormalities that may be involved in externalizing symptoms than structural imaging approaches. Further, SPECT results may be helpful in formulating effective treatment planning.
机译:收集了八名儿童和青少年(四个女孩;四个男孩;年龄从4至16岁)的诊断和背景数据,这些患者接受了小型精神病住院单元的神经成像检查。转诊问题与治疗的难治性以及脑外伤或神经发育问题的可能性有关。五名被诊断出患有胎儿酒精综合症的人,均表现出外向或行为不当。结构成像(磁共振成像或MRI)的结果表明,其中三个参与者明显发育不足或萎缩。功能性成像(单光子发射计算机断层扫描或SPECT)显示所有相关个体的左半球灌注不足。灌注不足的位置与冲动控制不佳的表现相一致,冲动控制是患者中常见的行为要素。研究结果表明,与结构成像方法相比,SPECT对可能涉及外在症状的细微脑部异常更为敏感。此外,SPECT结果可能有助于制定有效的治疗计划。

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