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首页> 外文期刊>Ultrasound in Medicine and Biology >Effects of ultrasound on osteotomy healing in a rabbit fracture model.
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Effects of ultrasound on osteotomy healing in a rabbit fracture model.

机译：超声对兔骨折模型截骨愈合的影响。

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摘要

This study investigated the effects of ultrasound (US) at different frequencies on fracture healing over a three-week period in a rabbit fibular fracture model. Forty-five adult New Zealand White rabbits were divided into five groups: a control group and four groups treated with US frequencies of 0.5, 1.0, 1.5 and 2.0 MHz (0.5 W/cm(2), 200-mus burst, pulsed 1:4). After anesthesia, transverse osteotomy was performed on the fibula bone. This was followed by intravital staining and fluorescence microscopic examination of new bone formation and biomechanical tests of torsional stiffness at the osteotomy site. Results showed that total new bone formation and torsional stiffness of the fibula were greater in all US-treated groups than in the control group. No significant difference was found between any of the four US-treated groups. The US treatment also enhanced bone growth of the sham-treated contralateral fracture site. These results suggest that US treatment at 0.5, 1.0, 1.5 or 2.0 MHz can enhance fracture healing in a rabbit model. Furthermore, the effects of US on fracture healing at present parameters might not be confined locally.
机译：这项研究调查了不同频率的超声（US）对兔腓骨骨折模型三周内骨折愈合的影响。四十五只成年新西兰白兔分为五组：对照组和四组，分别用美国的0.5、1.0、1.5和2.0 MHz（0.5 W / cm（2），200 mus脉冲，脉冲1： 4）。麻醉后，对腓骨进行横向截骨术。然后进行活体染色和新骨形成的荧光显微镜检查以及截骨部位扭转刚度的生物力学测试。结果显示，所有US治疗组的腓骨总新骨形成和扭转刚度均高于对照组。在接受美国治疗的四个组之间，没有发现显着差异。 US治疗还增强了假手术对侧骨折部位的骨生长。这些结果表明，在0.5、1.0、1.5或2.0 MHz的US治疗可以增强兔模型的骨折愈合。此外，在目前的参数下，US对骨折愈合的影响可能不会局限在局部。

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