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首页> 外文期刊>Ultrasound in Medicine and Biology >Novel tissue mimicking materials for high frequency breast ultrasound phantoms.
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Novel tissue mimicking materials for high frequency breast ultrasound phantoms.

机译：用于高频乳房超声幻象的新型组织模仿材料。

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摘要

The development and acoustical characterisation of a range of novel agar-based tissue mimicking material (TMMs) for use in clinically relevant, quality assurance (QA) and anthropomorphic breast phantoms are presented. The novel agar-based TMMs described in this study are based on a comprehensive, systematic variation of the ingredients in the International Electrotechnical Commission (IEC) TMM. A novel, solid fat-mimicking material was also developed and acoustically characterised. Acoustical characterisation was carried out using an in-house scanning acoustic macroscope at low (7.5 MHz) and high frequencies (20 MHz), using the pulse-echo insertion technique. The speeds of sound range from 1490 to 1570 m. s(-1), attenuation coefficients range from 0.1 to 0.9 dB. cm(1). MHz(-1) and relative backscatter ranges from 0 to -20 dB. It was determined that tissues can be mimicked in terms of independently controllable speeds of sound and attenuation coefficients. These properties make these novel TMMs suitable for use in clinically relevant QA and anthropomorphic phantoms and would potentially be useful for other high frequency applications such as intravascular and small animal imaging.
机译：介绍了一系列新型的基于琼脂的组织模拟材料（TMM）的开发和声学特性，这些材料可用于临床相关，质量保证（QA）和拟人化的乳房幻像。本研究中描述的新型琼脂基TMM是基于国际电工委员会（IEC）TMM中成分的全面，系统的变化。还开发了一种新型的模仿脂肪的固体材料，并进行了声学表征。使用脉冲回波插入技术，使用内部扫描声学宏观镜在低频（7.5 MHz）和高频（20 MHz）下进行声学表征。声速范围为1490至1570 m。 s（-1），衰减系数范围是0.1到0.9 dB。厘米（1）。 MHz（-1）和相对反向散射范围是0到-20 dB。已经确定，可以根据声音的独立速度和衰减系数来模仿组织。这些特性使这些新型TMM适合用于临床相关的QA和拟人化体模，并且可能对其他高频应用（例如血管内和小型动物成像）有用。

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