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首页> 外文期刊>Ultrasound in Medicine and Biology >Relationship between ultrasound texture classification images and histology of atherosclerotic plaque.
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Relationship between ultrasound texture classification images and histology of atherosclerotic plaque.

机译：超声纹理分类图像与动脉粥样硬化斑块组织学之间的关系。

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摘要

Structure and content of atherosclerotic plaque varies between patients and may be indicative of their risk for embolisation. This study aimed to construct parametric images of B-scan texture and assess their potential for predicting plaque morphology. Sequential transverse in vitro scans of 10 carotid plaques, excised during endarterectomy, were compared with macrohistology maps of plaque content. Multidiscriminant analysis combined the output of 157 statistical and textural algorithms into five separate texture classes, displayed as ultrasound (US) texture classification images (UTCI). Visual comparison between corresponding UTCI and histology maps found the five texture classes matched with the location of fibrin, elastin, calcium, haemorrhage or lipid. However, histology preparation removes calcium and lipid and, so, can affect the structural integrity of atherosclerotic plaques. Soft tissue regions smaller than the UTCI kernel, (0.87 mm x 0.85 mm x 3.9 mm), such as blood clots, are also difficult to detect by UTCI. These factors demonstrate limitations in the use of histology as a "gold standard" for US tissue characterisation.
机译：患者之间的动脉粥样硬化斑块的结构和含量不同，可能表明其发生栓塞的风险。这项研究旨在构建B扫描纹理的参数化图像并评估其预测斑块形态的潜力。将在动脉内膜切除术期间切除的10个颈动脉斑块的顺序横向体外扫描与斑块含量的宏观组织学图进行了比较。多判别分析将157种统计和纹理算法的输出组合成五个单独的纹理类别，以超声（US）纹理分类图像（UTCI）显示。相应的UTCI和组织学图谱之间的视觉比较发现，五个纹理类别与纤维蛋白，弹性蛋白，钙，出血或脂质的位置相匹配。但是，组织学准备会去除钙和脂质，因此会影响动脉粥样硬化斑块的结构完整性。小于UTCI内核（0.87 mm x 0.85 mm x 3.9 mm）的软组织区域（例如血块）也很难通过UTCI进行检测。这些因素证明了组织学作为美国组织表征的“金标准”使用的局限性。

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