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首页> 外文期刊>Ultrasound in Medicine and Biology >Correlations among critical closing pressure, pulsatility index and cerebrovascular resistance.
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Correlations among critical closing pressure, pulsatility index and cerebrovascular resistance.

机译：临界闭合压力，搏动指数和脑血管阻力之间的相关性。

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We attempted to explore the relationships among critical closing pressure (CrCP), resistance-area product (RAP) and traditional resistance indices of cerebral hemodynamics. Twenty healthy volunteers were studied. Blood pressure was obtained with servo-controlled plethysmography. Cerebral blood flow velocity (CBFV) was monitored by transcranial Doppler. Hemodynamic changes were induced by hyperventilation and by 5% CO(2) inhalation. Beat-to-beat CrCP and RAP values were extracted by linear regression analysis of instantaneous arterial blood pressure (ABP) and CBFV tracings. Gosling's pulsatility index (PI) and cerebrovascular resistance (CVR) were calculated. RAP correlated well with CVR at rest and during provocative tests (p = 0.006 approximately <0.001). There was no correlation among CrCP, CVR and PI. The changes in CVR correlated with those in RAP (p = 0.008 for the 5% CO(2) test and p = 0.014 for the hyperventilation test). The changes in PI and CrCP showed significant correlation (p = 0.004 for the 5% CO(2) test and p = 0.003 for the hyperventilation test). RAP reliably reflected cerebrovascular resistance. The changes in CrCP were valuable in assessing cerebrovascular regulation. Estimating changes in CrCP and RAP provided better understanding of the nature of cerebrovascular regulation. ().
机译：我们试图探索临界闭合压力（CrCP），阻力区域积（RAP）和传统脑血流动力学阻力指数之间的关系。研究了二十名健康志愿者。通过伺服控制体积描记法获得血压。通过经颅多普勒监测脑血流速度（CBFV）。换气过度和5％CO（2）吸入引起血流动力学变化。通过对瞬时动脉血压（ABP）和CBFV示踪的线性回归分析来提取逐搏CrCP和RAP值。计算了高斯林的搏动指数（PI）和脑血管阻力（CVR）。在休息和刺激性测试期间，RAP与CVR相关性很好（p = 0.006大约<0.001）。 CrCP，CVR和PI之间没有相关性。 CVR的变化与RAP相关（对于5％CO（2）测试，p = 0.008;对于过度换气测试，p = 0.014）。 PI和CrCP的变化显示出显着的相关性（对于5％CO（2）测试，p = 0.004;对于过度换气测试，p = 0.003）。 RAP可靠地反映了脑血管阻力。 CrCP的变化在评估脑血管调节方面很有价值。估计CrCP和RAP的变化可更好地了解脑血管调节的本质。 （）。

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