...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Ultrasound in Medicine and Biology >Subharmonic contrast intravascular ultrasound for vasa vasorum imaging.
【24h】

Subharmonic contrast intravascular ultrasound for vasa vasorum imaging.

机译：亚谐波造影剂血管内超声用于血管造影。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The feasibility of subharmonic contrast intravascular ultrasound (IVUS) imaging was investigated using a prototype nonlinear IVUS system and the commercial contrast agent Definity . The system employed a mechanically scanned commercial catheter with a custom transducer element fabricated to have sensitivity at both 15 and 30 MHz. Experiments were conducted at a fundamental frequency of 30 MHz (F30; 25% bandwidth), with on-axis pressures ranging from 0.12 to 0.79 MPa, as measured with a needle hydrophone. In vitro characterization experiments demonstrated the detection of 15 MHz subharmonic signals (SH15) when pressure levels reached 360 kPa. The formation of SH15 images was shown, with tissue signals suppressed to near the noise floor and contrast to tissue ratios were improved by up to 30 dB relative to F30. In vivo experiments were performed using the atherosclerotic rabbit aorta model. Following the bolus injection of contrast agent upstream of the imaging catheter, agent was detected within the aorta, vena cava and within the perivascular space. These results provide a first in vivo demonstration of subharmonic contrast IVUS and suggest its potential as a new technique for imaging vasa vasorum.
机译：使用原型非线性IVUS系统和商用造影剂Definity，研究了亚谐波造影剂血管内超声（IVUS）成像的可行性。该系统采用机械扫描的商用导管，该导管带有定制的换能器元件，可制作成在15和30 MHz均具有灵敏度。实验是在30 MHz（F30; 25％带宽）的基频上进行的，其轴向压力在0.12到0.79 MPa之间，这是用针式水听器测量的。体外表征实验表明，当压力水平达到360 kPa时，可以检测到15 MHz的亚谐波信号（SH15）。示出了SH15图像的形成，其中组织信号被抑制到接近本底噪声，并且相对于F30，与组织的比率的对比度提高了多达30 dB。使用动脉粥样硬化兔主动脉模型进行体内实验。在成像导管上游大剂量注射造影剂后，在主动脉，腔静脉和血管周间隙内检测到造影剂。这些结果提供了亚谐波造影剂IVUS的首次体内证明，并暗示了其作为血管脉管成像的新技术的潜力。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号