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首页> 外文期刊>Ultrasound in Medicine and Biology >Glycemia, lipidemia and systolic left ventricular function evaluated by myocardial strain rate: a tissue Doppler echocardiographic study.
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Glycemia, lipidemia and systolic left ventricular function evaluated by myocardial strain rate: a tissue Doppler echocardiographic study.

机译:通过心肌应变率评估血糖,血脂和收缩期左心室功能:组织多普勒超声心动图研究。

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摘要

Recent studies have indicated that hyperglycemia and insulin resistance are significantly correlated to left ventricular (LV) long-axis function, and it seems that optimized glycemic control is significantly related to improved LV function. The aim of the study was to investigate the relation between glucose metabolism, lipid levels and LV long-axis function in normal subjects. The study population consisted of 20 unselected male patients, free of medication and without history of cardiac disease. The main outcome measures were LV systolic strain rate in the long-axis plane, examined by tissue Doppler echocardiography and fasting values of plasma glucose, insulin, cholesterol and triglycerides. The mean systolic strain rate was found to correlate significantly to age (r(2) = 0.34, p < 0.01), fasting blood glucose levels (r(2) = 0.25, p < 0.01) and low-density lipoprotein (LDL) cholesterol levels (r(2) = 0.38, p < 0.01). however, did not correlate significantly to traditional measures of insulin resistance like truncal body fat, fasting insulin or triglyceride levels. In conclusion, LV systolic function seems significantly related to fasting levels of glucose and LDL cholesterol in normal subjects.
机译:最近的研究表明,高血糖和胰岛素抵抗与左心室(LV)长轴功能显着相关,并且似乎最佳的血糖控制与改善的LV功能显着相关。该研究的目的是研究正常人的葡萄糖代谢,脂质水平和左室长轴功能之间的关系。研究人群包括20名未经选择的男性患者,他们没有药物治疗,也没有心脏病史。主要结果指标是通过组织多普勒超声心动图检查以及血浆葡萄糖,胰岛素,胆固醇和甘油三酸酯的空腹值,检查了长轴平面内的左室收缩收缩率。发现平均收缩压率与年龄(r(2)= 0.34,p <0.01),空腹血糖水平(r(2)= 0.25,p <0.01)和低密度脂蛋白(LDL)胆固醇显着相关水平(r(2)= 0.38,p <0.01)。但是,它与传统的胰岛素抵抗指标(如截断的体脂,空腹胰岛素或甘油三酸酯水平)没有显着相关。总之,正常人的左室收缩功能似乎与空腹血糖和低密度脂蛋白胆固醇显着相关。

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