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首页> 外文期刊>Ultrasound in Medicine and Biology >Identifying elderly women with osteoporosis by spinal dual X-ray absorptiometry, calcaneal quantitative ultrasound and spinal quantitative computed tomography: a comparative study.
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Identifying elderly women with osteoporosis by spinal dual X-ray absorptiometry, calcaneal quantitative ultrasound and spinal quantitative computed tomography: a comparative study.

机译：脊柱双重X线骨密度仪，跟骨定量超声检查和脊柱定量计算机断层扫描确定患有骨质疏松症的老年妇女：一项比较研究。

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摘要

The ability of spinal dual x-ray absorptiometry (DXA), calcaneal quantitative ultrasound (QUS) and spinal quantitative computed tomography (QCT) to identify women with osteoporosis within the GISELA study was evaluated in 43 women, aged 62-87 years. Osteoporosis was defined as a T-score below or equal to -2.5 using DXA (femoral neck). To determine the performance of each method, the sensitivity, specificity and area under the curve (by means of a receiver operating characteristic [ROC] analysis) were calculated. The median T-scores from the measurements differed significantly (p < 0.0001). DXA (spine) identified 75% of women with osteoporosis; QUS and QCT identified 100%. The specificity was 89% for DXA (spine), 66% for QUS and 29% for QCT. ROC analysis showed that all three methods are qualified to identify women with osteoporosis; however, the different sensitivities and specificities of the methods, as well as the thresholds used for diagnosing osteoporosis have to be considered.
机译：在GISELA研究中，对43位62-87岁的女性进行了脊柱X线骨密度仪（DXA），跟骨定量超声（QUS）和脊柱定量计算机断层扫描（QCT）识别骨质疏松妇女的能力的评估。骨质疏松症定义为使用DXA（股骨颈）的T评分低于或等于-2.5。为了确定每种方法的性能，计算了灵敏度，特异性和曲线下面积（通过接收器工作特征[ROC]分析）。测量结果的中位T分差异显着（p <0.0001）。 DXA（脊柱）识别出75％的骨质疏松症女性; QUS和QCT确定为100％。 DXA（脊柱）的特异性为89％，QUS的特异性为66％，QCT的特异性为29％。 ROC分析表明，这三种方法均可以鉴定出患有骨质疏松症的女性;但是，必须考虑该方法的不同敏感性和特异性，以及用于诊断骨质疏松症的阈值。

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