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首页> 外文期刊>Ultrasound in Medicine and Biology >Contrast-Enhanced Intravascular Ultrasound Pulse Sequences for Bandwidth-Limited Transducers
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Contrast-Enhanced Intravascular Ultrasound Pulse Sequences for Bandwidth-Limited Transducers

机译：带宽受限换能器的增强造影剂的血管内超声脉冲序列

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摘要

We demonstrate two methods for vasa vasorum imaging using contrast-enhanced intravascular ultrasound, which can be performed using commercial catheters. Plaque neovascularization was recognized as an independent marker of coronary artery plaque vulnerability. IVUS-based methods to image the microvessels available to date require high bandwidth (-6 dB relative frequency bandwidth >70%), which are not routinely available commercially. We explored the potential of ultraharmonic imaging and chirp reversal imaging for vasa vasorum imaging. In vitro recordings were performed on a tissue-mimicking phantom using a commercial ultrasound contrast agent and a transducer with a center frequency of 34 MHz and a -6 dB relative bandwidth of 56%. Acoustic peak pressures <500 kPa were used. A tissue-mimicking phantom with channels down to 200 μm in diameter was successfully imaged by the two contrast detection sequences while the smallest channel stayed invisible in conventional intravascular ultrasound images. Ultraharmonic imaging provided the best contrast agent detection.
机译：我们演示了使用造影剂增强型血管内超声对脉管血管成像的两种方法，可以使用商业导管进行。斑块新血管形成被认为是冠状动脉斑块易损性的独立标志。迄今为止，基于IVUS的使微血管成像的方法需要高带宽（-6 dB相对频率带宽> 70％），而这通常是商业上无法获得的。我们探索了超谐波成像和线性调频反向成像在脉管血管成像中的潜力。使用商业超声造影剂和具有34 MHz中心频率和-6 dB相对带宽56％的换能器在模仿组织的体模上进行体外记录。使用小于500 kPa的声峰值压力。通过两个对比检测序列成功地成像了直径小于200μm的组织模仿体模，而最小的通道在常规血管内超声图像中保持不可见。超谐波成像可提供最佳的造影剂检测。

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