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首页> 外文期刊>Ultrasound in Medicine and Biology >Can contrast-enhanced ultrasound distinguish malignant from reactive lymph nodes in patients with head and neck cancers?
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Can contrast-enhanced ultrasound distinguish malignant from reactive lymph nodes in patients with head and neck cancers?

机译：超声造影能否将头颈部癌患者的恶性淋巴结与反应性淋巴结区分开？

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摘要

The purpose of this study was to investigate the utility of contrast-enhanced ultrasound in differentiating benign from malignant cervical lymph nodes in patients with squamous cell carcinoma of the head and neck. A consecutive series of 17 patients with known head and neck malignancy scheduled for neck surgery and lymph node clearance were recruited for contrast-enhanced ultrasound evaluation. Sonographic signal intensity as a function of time, comparing features of time to peak, time to arrival and time to wash-out, was quantified. The selected node was removed surgically and submitted for histology. Contrast-enhanced ultrasound examination had 100% sensitivity and 85.7% specificity for lymph node involvement. Functional analysis revealed contrast peaks significantly earlier in the malignant nodes (mean±standard deviation) of 24.14±2.7 s compared with 29.33±3.4 s (p=0.0128). Contrast-enhanced ultrasound holds promise in the detection and characterization ofmetastatic nodes that would not be diagnosed as abnormal on the basis of conventional ultrasound criteria.
机译：这项研究的目的是探讨在头颈部鳞状细胞癌患者中，超声造影在区分良性和恶性宫颈淋巴结中的作用。连续收集了17例计划进行颈部手术和淋巴结清除术的已知头颈部恶性肿瘤患者，以进行超声造影评估。超声信号强度作为时间的函数，比较了到达峰值时间，到达时间和冲洗时间的特征。选定的结节通过外科手术切除并提交组织学检查。超声造影检查对淋巴结受累的敏感性为100％，特异性为85.7％。功能分析显示，在恶性淋巴结中，造影剂峰明显提前（平均值±标准差）为24.14±2.7 s，而在29.33±3.4 s时（p = 0.0128）。对比增强的超声在检测和鉴定转移性结节方面有希望，根据常规超声标准，这些结节不会被诊断为异常。

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