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首页> 外文期刊>Urology >Predicting the Histology of Small Renal Masses Using Preoperative Dynamic Contrast-enhanced Magnetic Resonance Imaging
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Predicting the Histology of Small Renal Masses Using Preoperative Dynamic Contrast-enhanced Magnetic Resonance Imaging

机译：术前动态对比增强磁共振成像预测小肾脏肿块的组织学

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To study whether magnetic resonance imaging can predict the histologic type of small renal cell carcinoma.Dynamic contrast-enhanced magnetic resonance imaging was performed in 63 patients with computed tomography- or ultrasonography-suspected small (<=4 cm) renal cell carcinoma from February 2008 to February 2010. Percentage signal intensity change, tumor-to-cortex enhancement index during precontrast phase, corticomedullary phase, and nephrogenic phase were investigated.Among the 60 patients, 42 were proven to have clear cell renal cell carcinoma and 18 patients were proven to have non-clear cell renal cell carcinoma (10 patients with papillary renal cell carcinoma, 8 patients with chromophobe renal cell carcinoma). The percentage signal intensity change in the clear cell type was higher only in the corticomedullary phase (P = .002). The tumor-to-cortex enhancement index in the clear cell type was higher in the corticomedullary and nephrogenic phases (P = .007 and P = .041, respectively). The most valuable marker was percentage signal intensity change in the corticomedullary phase (area under the receiver operating characteristic curve 0.85). The cut-off value of percentage signal intensity change in the corticomedullary phase was 173%, and the sensitivity and specificity were 81% and 87.5%, respectively.Dynamic contrast-enhanced magnetic resonance imaging could be useful for discriminating the clear cell type from non-clear cell type in small renal cell carcinoma with high sensitivity and specificity.
机译：研究磁共振成像是否可以预测小肾细胞癌的组织学类型。自2008年2月起，对63例计算机X线或超声检查怀疑的小（<= 4 cm）肾细胞癌患者进行了动态对比增强磁共振成像到2010年2月，研究了造影剂前期，皮质肾小球期和肾源性阶段的信号强度变化百分比，肿瘤-皮层增强指数。在60例患者中，有42例被证实患有透明细胞肾细胞癌，有18例被证实患有肾透明细胞癌。患有非透明细胞肾细胞癌（10例乳头状肾细胞癌，8例发色性肾细胞癌）。透明细胞类型中的信号强度变化百分比仅在皮质髓质期较高（P = .002）。在皮质髓质和肾生成期，透明细胞类型的肿瘤至皮质增强指数较高（分别为P = .007和P = .041）。最有价值的标记是皮质肾小管相（接收器工作特性曲线下的区域0.85）的信号强度变化百分比。皮质髓质期信号强度变化百分比的临界值为173％，灵敏度和特异性分别为81％和87.5％。动态对比增强磁共振成像可用于区分透明细胞类型和非透明细胞类型。肾细胞癌中的透明细胞类型具有高敏感性和特异性。

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