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Incidence of benign pathologic findings at partial nephrectomy for solitary renal mass presumed to be renal cell carcinoma on preoperative imaging.

机译:在术前影像检查中,部分肾切除术中孤立性肾脏肿块的良性病理发现发生率推测为肾细胞癌。

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摘要

OBJECTIVES: To determine the incidence of benign pathologic findings at partial nephrectomy for a solitary renal lesion when preoperative imaging is reviewed by an experienced team of academic genitourinary radiologists. METHODS: From 1996 to 2004, 143 patients underwent resection of a solitary renal lesion for presumed renal cell carcinoma amenable to partial nephrectomy. Our experienced team of genitourinary radiologists interpreted all preoperative imaging scans. Of the 143 patients, 44 underwent partial nephrectomy for a solitary lesion less than 2 cm, 85 for a lesion 2 to 4 cm, and 14 for a lesion greater than 4 cm. RESULTS: Of the 143 solitary masses resected, 23 revealed benign pathologic findings (16.1%). Ten lesions (43.5%) were angiomyolipomas (AMLs), eight (34.8%) were oncocytomas, three (13.0%) were benign Bosniak-type cysts, and one each was a low-grade spindle cell lesion most consistent with mesoblastic nephroma, and a metanephric adenoma. CONCLUSIONS: A significant fraction of small solitary renal masses presumed to be renal cell carcinoma had benign pathologic findings on resection, despite thorough expert radiologic review. Management should favor parenchyma-sparing approaches, because resection serves not only a therapeutic but also a diagnostic function. Patients should be counseled accordingly when faced with the diagnosis of renal mass.
机译:目的:当经验丰富的泌尿生殖放射学专家小组对术前影像进行检查时,确定部分肾切除术对单发性肾脏病变的良性病理发现的发生率。方法:从1996年至2004年,对143例因推测为适合部分肾切除术的肾细胞癌的单个肾病变进行了切除。我们经验丰富的泌尿生殖放射科医生团队对所有术前影像扫描进行了解释。在这143例患者中,有44例行部分肾切除术治疗的病灶小于2 cm,85例病灶为2至4 cm,14例病灶大于4 cm。结果:在切除的143例孤立性肿块中,有23例显示出良性病理结果(16.1%)。血管平滑肌脂肪瘤(AML)占10个病变(43.5%),肿瘤细胞瘤占8个(34.8%),良性Bosniak型囊肿占3个(13.0%),每个病变是与中胚层性肾瘤最一致的低度梭形细胞病变,和后肾腺瘤。结论:尽管经过全面的放射学专家检查,但仍有相当一部分被认为是肾细胞癌的孤立性小肾脏肿块有良性病变。管理层应支持保留实质的方法,因为切除术不仅具有治疗作用,而且具有诊断功能。面对肾脏肿块的诊断时,应相应建议患者。

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