...
首页> 外文期刊>Urology >A method for estimating within-patient variability in maximal urinary flow rate adjusted for voided volume.
【24h】

A method for estimating within-patient variability in maximal urinary flow rate adjusted for voided volume.

机译:一种用于估计针对排尿量调整的最大尿流率的患者内变异性的方法。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       

摘要

OBJECTIVES: To investigate whether volume adjustment can be used to reduce the within-patient variability of the maximal urinary flow rate (Qmax) without affecting the variability between patients. METHODS: We analyzed 2049 urinary flow curves of 208 men with lower urinary tract symptoms suggestive of bladder outlet obstruction and studied the relation between Qmax and voided volume (VV) in individual patients using multilevel regression analysis. RESULTS: In agreement with most previous studies, we found a hyperbolic relation between the VV and Qmax. Although hyperbolic on average, the slope of the regression line relating the VV to Qmax differed substantially across individual patients. In some patients, Qmax even tended to be lower with an increased VV. CONCLUSIONS: The reproducibility of Qmax is poor, in part because of its dependence on the VV. The current methods to adjust Qmax for VV, such as the Siroky nomogram, minimize between-patient dependency, whereas our findings emphasize the importance of within-patient variability. A common approach to adjust Qmax for VV, however, is not feasible, because the relation of Qmax to VV differs substantially across patients. The only valid, although impractical option, remains to record a large number of urinary flow curves for each patient.
机译:目的:探讨是否可以使用体积调节来减少最大尿流率(Qmax)的患者内部变异性,而不影响患者之间的变异性。方法:我们分析了208例下尿路症状提示膀胱出口阻塞的男性的2049条尿流曲线,并使用多级回归分析研究了个体患者的Qmax与排尿量(VV)之间的关系。结果:与大多数以前的研究一致,我们发现VV和Qmax之间存在双曲线关系。尽管平均而言是双曲线的,但在各个患者中,将VV与Qmax相关的回归线的斜率存在很大差异。在某些患者中,随着VV的增加,Qmax甚至趋于降低。结论:Qmax的重现性较差,部分原因是其对VV的依赖性。 Sirovy nomogram等目前为VV调整Qmax的方法可最大程度地减少患者之间的依赖性,而我们的发现则强调了患者内部变异的重要性。但是,调整Vmax的Qmax的通用方法是不可行的,因为Qmax与VV的关系在不同患者之间存在很大差异。尽管不切实际,但唯一有效的选择仍然是为每位患者记录大量的尿流曲线。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号