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首页> 外文期刊>Urology >Relationship between patient self-assessment of erectile function and the erectile function domain of the international index of erectile function.
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Relationship between patient self-assessment of erectile function and the erectile function domain of the international index of erectile function.

机译:患者勃起功能自我评估与勃起功能国际指数的勃起功能域之间的关系。

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摘要

OBJECTIVES: To assess the validity of severity classes on the erectile function (EF) domain of the International Index of Erectile Function by determining their relationship with the self-assessment of EF, before and after treatment, in an independent cohort of patients. METHODS: Two hundred forty-seven men with clinically diagnosed erectile dysfunction (ED) and in a stable heterosexual relationship were enrolled in a randomized, double-blind, multicenter, placebo-controlled, parallel-group, 12-week, flexible-dose study. Patients assessed their degree of ED as severe, moderate, minimal/mild, or no problem at baseline and after treatment. They also responded to the six questions of the EF domain, with the total score indicating the following degrees of ED: severe, EF score 1 to 10; moderate, EF score 11 to 16; mild to moderate, EF score 17 to 21; mild, EF score 22 to 25; and no ED, EF score 26 to 30. Descriptive profiles of the two diagnostic instruments were compared. The correlations between the instruments were evaluated with Kendall's tau-b at baseline, after treatment at 12 weeks, and at change from baseline. RESULTS: The two measures gave generally similar descriptive profiles of ED severity. The correlations were 0. 65 (95% confidence interval 0.57 to 0.73) at baseline, 0.86 (95% confidence interval 0.83 to 0.89) after 12 weeks of treatment, and 0. 73 (95% confidence interval 0.67 to 0.79) at change from baseline. CONCLUSIONS: The moderate-to-high correlation between the patients' self-assessment of EF and the EF domain of the International Index of Erectile Function provides a validation of this domain for the reliable diagnostic classification of ED severity.
机译:目的:通过在独立队列研究中确定治疗前和治疗后它们与EF自我评估的关系,来评估国际勃起功能指数中勃起功能(EF)领域严重程度类别的有效性。方法:对247名经临床诊断为勃起功能障碍(ED)和异性恋关系稳定的男性进行了一项随机,双盲,多中心,安慰剂对照,平行组,12周,灵活剂量的研究。患者在基线和治疗后评估其ED程度为严重,中度,最小/轻度或无问题。他们还回答了EF域的六个问题,总分表明了以下ED程度:严重,EF得分为1至10; EF为1。中度,EF分数11至16;轻度至中度,EF评分为17-21;轻度,EF评分为22到25;没有ED,EF得分为26到30。比较了两种诊断工具的描述性特征。基线,治疗12周后和基线变化后,用Kendall tau-b评估仪器之间的相关性。结果:两种方法给出了ED严重程度的大致描述性概况。相关性在基线时为0. 65(95%置信区间为0.57至0.73),在治疗12周后为0.86(95%置信区间为0.83至0.89)和在变化后为0. 73(95%置信区间0.67至0.79)。基线。结论:患者自我评估的EF与国际勃起功能指数的EF域之间的中度至高度相关性为可靠的ED严重程度的诊断分类提供了对该域的验证。

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