Redox-Induced Binding of [(tacn)(ReBr)-Br-II(CO)(2)](+) to Guanine, Oligonucleotides, and Peptides

Zobi F; Alberto R

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Redox-Induced Binding of [(tacn)(ReBr)-Br-II(CO)(2)](+) to Guanine, Oligonucleotides, and Peptides

机译：氧化还原诱导的[（tacn）（ReBr）-Br-II（CO）（2）]（+）与鸟嘌呤，寡核苷酸和肽的结合

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Drug discovery and development based on purely organic molecules is a main focus of pharmaceutical research in industries and at universities. Motivated by the impact of cisplatin and its successors, metal-based drug research persists as an incentive and an innovative field with many facets.[1–3] A growing number of comprehensive reviews underscores the vivid research carried out with metals in medicine.[4–8] When designing metal-based drugs, not only structural aspects have to be taken into account.

机译：基于纯有机分子的药物发现和开发是工业和大学中药物研究的主要重点。受顺铂及其后续产品的影响，基于金属的药物研究一直是一个激励因素，也是一个具有许多方面的创新领域。[1-3]越来越多的综合综述强调了在医学中对金属进行的生动研究。[ [4-8]在设计金属基药物时，不仅必须考虑结构方面。

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《Chemistry: A European journal》 |2010年第9期|共4页
作者
Zobi F; Alberto R;
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正文语种 eng
中图分类应用化学;
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development; successors; research;

机译：发展;成功者;研究;

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1. Redox-Induced Binding of [(tacn)(ReBr)-Br-II(CO)(2)](+) to Guanine, Oligonucleotides, and Peptides [J] . Zobi F, Alberto R Chemistry: A European journal . 2010,第9期

机译：氧化还原诱导的[（tacn）（ReBr）-Br-II（CO）（2）]（+）与鸟嘌呤，寡核苷酸和肽的结合
2. Synthesis and Reactivity of the 17 e(-) Complex [(ReBr4)-Br-II(CO)(2)](2-): A Convenient Entry into Rhenium(II) Chemistry [J] . Zobi F, Kromer L, Spingler B, Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics . 2009,第18期

机译：17 e（-）配合物[（ReBr4）-Br-II（CO）（2）]（2-）的合成和反应性：Entry化学的便捷输入
3. Characterization of Lysine-Guanine Cross-Links upon One-Electron Oxidation of a Guanine-Containing Oligonucleotide in the Presence of a Trilysine Peptide [J] . Sandrine Perrier, Jorg Hau, Didier Gasparutto, Journal of the American Chemical Society . 2006,第17期

机译：在赖氨酸肽存在的情况下一个鸟嘌呤的寡核苷酸的单电子氧化赖氨酸-鸟嘌呤交联的表征。
4. Reactivity of nitrogen mustards towards guanines adjacent to methylated cytosines in oligonucleotides [C] . Suncerae I. Smith, Jennifer S. Brodbelt ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：少核苷酸邻近甲基化胞嘧啶邻近甲基化胞嘧啶的亚硝芥末的反应性
5. Optimization of Guanine Quadruplex-targeted Peptide Nucleic Acids. [D] . Murphy, Connor T. 2010

机译：鸟嘌呤四链体靶向肽核酸的优化。
6. Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue and correlation with mutation frequency [O] . Kentaro Taira, Shintaro Nakamura, Khota Nakano, -1

机译：MutS蛋白与含有甲基化或乙基化鸟嘌呤残基的寡核苷酸的结合并与突变频率相关
7. Identification of the guanine binding domain peptide of the GTP-binding site of glucagon. [O] . Shoemaker, M., Lin, P. C., Haley, B. 1992

机译：鉴定胰高血糖素的GTP结合位点的鸟嘌呤结合域肽。

Redox-Induced Binding of [(tacn)(ReBr)-Br-II(CO)(2)](+) to Guanine, Oligonucleotides, and Peptides

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