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Relation of urinary stone disease with androgenetic alopecia and serum testosterone levels

机译:泌尿系结石与雄激素性脱发和血清睾丸激素水平的关系

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摘要

We aimed to investigate the relationship among urinary stone disease, androgenetic alopecia (AGA), and serum testosterone (T) levels. Between January 2008 and November 2015, we retrospectively investigated the biochemical parameters and anthropometric characteristics (height and weight) of 200 patients who had urinary tract stones. For the control group, we selected at random 168 participants who had no history of urolithiasis. Demographic data, such as participants' age, body mass index (BMI), hypertension (HT), diabetes mellitus (DM), baldness pattern, and serum T level were recorded. All participants were male, over 18 and under 60 years of age. We determined that risk of urolithiasis increased 1.3-fold in patients with vertex pattern alopecia and 2.1-fold in patients with total alopecia compared with those with no hair loss. In the severe balding Groups (Group III and Group IV), presence of testosterone deficiency was more frequent in patients with urinary stone disease (P = 0.041, OR = 2.38). Although in the non- balding and mild balding Groups (Group I and Group II), presence of testosterone deficiency was also more frequent in patients with urinary stone disease, a statistically significant difference was not seen. Significantly, we found that the presence of testosterone deficiency was more frequent in patients with urinary stone disease and who had severe AGA.
机译:我们旨在研究尿路结石疾病,雄激素性脱发(AGA)和血清睾丸激素(T)水平之间的关系。在2008年1月至2015年11月之间,我们回顾性调查了200例尿路结石患者的生化参数和人体测量学特征(身高和体重)。对于对照组,我们随机选择了168名没有尿石症病史的参与者。记录人口统计数据,例如参与者的年龄,体重指数(BMI),高血压(HT),糖尿病(DM),秃发模式和血清T水平。所有参与者均为男性,年龄在18岁以上,年龄在60岁以下。我们确定,与没有脱发的患者相比,具有顶点型脱发的患者尿路结石的风险增加了1.3倍,而具有全脱发的患者尿路结石的风险增加了2.1倍。在严重秃顶组(III组和IV组)中,泌尿系结石患者睾丸激素缺乏症的发生率更高(P = 0.041,OR = 2.38)。尽管在非秃顶和轻秃顶组(I组和II组)中,泌尿系结石患者的睾丸激素缺乏症也更为常见,但未见统计学上的显着差异。重要的是,我们发现泌尿系结石病患者和严重AGA患者睾丸激素缺乏症的发生率更高。

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