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首页> 外文期刊>Plastic surgical nursing: official journal of the American Society of Plastic and Reconstructive Surgical Nurses >Plastic surgery ethics: beyond face value.
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Plastic surgery ethics: beyond face value.

机译：整形外科伦理：超越面子。

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摘要

Prominent eyelashes are generally recognized as enhancing beauty and are often desired by women. Until recently, the options available to augment the prominence of eyelashes were limited to makeup, over-the-counter products, artificial eyelashes, and eyelash transplantation. Originally approved for the treatment of ocular hypertension, the prostamide, bimatoprost, is now approved for the treatment of hypotrichosis of the eyelashes. Bimatoprost ophthalmic solution 0.03%, applied once daily to the skin of the upper eyelid margin using sterile single-use-per-eye applicators, increases eyelash growth, including length, thickness, and darkness. The effectiveness of bimatoprost for eyelash growth has been demonstrated by clinician ratings, digital image analysis, and patient-reported measures of satisfaction. The effects of bimatoprost treatment on eyelash length, thickness, and darkness are believed to result from longer anagen duration, increased hair bulb thickness, and increased melanogenesis, respectively. Dermally applied bimatoprost appears to be associated with a lower incidence of adverse events than administration of the medication as an eyedrop. This more favorable safety and tolerability profile is likely mediated by decreased exposure of ocular tissues to bimatoprost when applied dermally. Taken together, available data suggest that cutaneous application of bimatoprost ophthalmic solution 0.03% safely and effectively enhances upper eyelash growth.
机译：众所周知，突出的睫毛可增强美感，是女性经常需要的。直到最近，增加睫毛突出度的可用选项还仅限于化妆，非处方产品，人造睫毛和睫毛移植。最初被批准用于治疗高眼压的药，前列腺素，比马前列酮现在被批准用于治疗睫毛的毛发过少。 0.03％的比马前列素眼用溶液，每天使用无菌的单眼一次性涂抹器涂抹在上眼睑边缘的皮肤上，可增加睫毛的生长，包括长度，厚度和暗度。临床医师评定，数字图像分析和患者报告的满意度测验证明了比马前列素对睫毛生长的有效性。据信比马前列素治疗对睫毛长度，厚度和暗沉的影响分别是由于较长的生长期，毛发粗细增加和黑色素生成增加所致。皮肤上施用比马前列素似乎与以眼药水形式给药相比，不良事件发生率更低。这种更有利的安全性和耐受性特征可能是通过皮肤施用时眼组织暴露于比马前列素的减少而介导的。综上所述，现有数据表明，经皮肤应用0.03％的比马前列素眼用溶液可安全有效地促进上睫毛的生长。

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