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首页> 外文期刊>Pathology International >Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin.
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Angiomatoid fibrous histiocytoma with cystic structures of sweat duct origin.

机译：具有汗管起源的囊性结构的类血管瘤纤维组织细胞瘤。

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摘要

Angiomatoid fibrous histiocytoma is an unusual soft tissue tumor, mostly arising in the subcutaneous fibro-adipose tissue of children and young adults and measuring a few centimeters in greatest dimension. Reported herein is a unique case of angiomatoid fibrous histiocytoma containing epithelium-lined cystic structures. This large tumor (12 cm) was located in the subcutaneous tissue of the left leg of a 28-year-old woman. The cystic structures were variably sized and were lined by a double cell layer with areas of squamous metaplasia. Their overall histological features suggested a sweat duct origin. Immunohistochemical stains confirmed such origin, demonstrating an inner epithelial and an outer myoepithelial (smooth muscle actin and cytokeratin 17 positive) cell layer. The present case is illustrative of a mechanism of sweat duct dilatation that may occur during the growth of neoplasms involving the dermis and subcutis, resulting in formation of tumors with unusual histological features.
机译：血管瘤样纤维组织细胞瘤是一种不常见的软组织肿瘤，多发于儿童和年轻人的皮下纤维脂肪组织，最大尺寸为几厘米。本文报道的是包含上皮衬里的囊性结构的血管瘤样纤维组织细胞瘤的独特病例。这个大肿瘤（12厘米）位于一名28岁妇女的左腿皮下组织中。囊性结构的大小各不相同，并由具有鳞状化生区域的双细胞层排列。它们的整体组织学特征表明汗管起源。免疫组织化学染色证实了这种来源，表明内部上皮和外部上皮（平滑肌肌动蛋白和细胞角蛋白17阳性）细胞层。本例说明了在涉及真皮和皮下组织的肿瘤生长过程中可能发生的汗管扩张机制，从而导致形成具有异常组织学特征的肿瘤。

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