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首页> 外文期刊>Pathology International >Extra-abdominal desmoid tumor presenting as an intrathoracic tumor: case report and literature review.
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Extra-abdominal desmoid tumor presenting as an intrathoracic tumor: case report and literature review.

机译:腹腔外类瘤表现为胸腔内肿瘤:病例报告及文献复习。

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摘要

A case of an extra-abdominal desmoid tumor presenting as an intrathoracic tumor (intrathoracic desmoid tumor) in a 46-year-old woman is reported. The tumor originated in the left chest wall and protruded into the left pleural cavity. Simple resection was carried out. The tumor, measuring 13 x 9 x 7 cm, was solid, gray-tan in color, and covered with parietal pleura. Histologically, the tumor was composed of a hypocellular arrangement of spindle-shaped cells with a fibromyxoid background. In some areas, keloid-like hyalinized collagen fibers proliferated, and a perivascular hypercellular area was seen. Immunohistochemical analysis showed that the cytoplasms of the tumor cells were strongly positive for vimentin, and some tumor cells were positive for alpha-smooth muscle actin, but all tumor cells were negative for CD34. These findings were consistent with the characteristics of an intrathoracic desmoid tumor. The differential diagnoses, in particular solitary fibrous tumor and tumors with a myofibroblastic nature, are discussed.
机译:据报道,在46岁的女性中,腹外结石样肿瘤表现为胸腔内肿瘤(胸内结石样肿瘤)。肿瘤起源于左胸壁并伸入左胸膜腔。简单切除。肿瘤长13 x 9 x 7厘米,是实心的,颜色为棕褐色,并被顶叶胸膜覆盖。从组织学上讲,该肿瘤由纺锤状细胞的低细胞排列组成,具有纤维粘胶样背景。在某些区域,瘢痕loid样的透明化胶原纤维增生,并观察到血管周围的细胞过多区域。免疫组织化学分析显示,肿瘤细胞的胞浆中波形蛋白强阳性,一些肿瘤细胞中α-平滑肌肌动蛋白阳性,而所有肿瘤细胞中CD34阴性。这些发现与胸腔内类胶质瘤的特征一致。讨论了鉴别诊断,特别是孤立性纤维性肿瘤和具有肌成纤维细胞性质的肿瘤。

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