Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer

Santucci Kimberly L.; Baust John M.; Snyder Kristi K.; Van Buskirk Robert G.; Baust John G.

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Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer

机译：细胞周期阶段对雄激素不敏感前列腺癌的冻结反应敏感性影响的研究

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Background: Cryoablation, an effective means of ablating cancer, is often used in conjunction with adjuvants that target cancer cells in a specific cell cycle stage to increase treatment efficacy. The objective of this study was to investigate the impact of cell cycle stage on cancer freeze response as well as investigate the potential cellular kinetic effect of calcitriol, the active metabolic of vitamin D-3, when used as a cryosensitizing adjuvant in order to maximize prostate cancer cell death.

机译：背景：冷冻消融是消融癌症的有效手段，通常与在特定细胞周期阶段靶向癌细胞的佐剂结合使用，以提高治疗效果。这项研究的目的是研究细胞周期阶段对癌症冻结反应的影响，以及当将钙三醇用作冷冻增敏佐剂以使前列腺最大化时，研究钙三醇的潜在细胞动力学作用，维生素D-3的活性代谢。癌细胞死亡。

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《Technology in cancer research & treatment.》 |2016年第4期|共9页
作者
Santucci Kimberly L.; Baust John M.; Snyder Kristi K.; Van Buskirk Robert G.; Baust John G.;
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正文语种 eng
中图分类肿瘤学;
关键词
cell cycle; prostate cancer; cryosurgery; vitamin D3; synchronization;

机译：细胞周期;前列腺癌;冷冻手术;维生素D3;同步化;

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1. Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer [J] . Santucci Kimberly L., Baust John M., Snyder Kristi K., Technology in cancer research & treatment. . 2016,第4期

机译：细胞周期阶段对雄激素不敏感前列腺癌的冻结反应敏感性影响的研究
2. Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer [J] . Kimberly L. Santucci, John M. Baust, Kristi K. Snyder, Technology in cancer research & treatment. . 2016,第4期

机译：细胞周期阶段对雄激素不敏感前列腺癌的冻结反应敏感性影响的研究
3. Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer [J] . Kimberly L. Santucci, John M. Baust, Kristi K. Snyder, Technology in cancer research & treatment. . 2016,第4期

机译：细胞周期阶段对雄激素不敏感前列腺癌的冻结反应敏感性影响的研究
4. Arsenic trioxide enhances radiation sensitivity of androgendependent and -independent human prostate cancer cells [C] . Ying-Jan Wang, Hui-Wen Chiu, Yi-An Chen, International Congress Arsenic In The Environment . 2012

机译：三氧化砷增强了雄性义义彼德和依赖性人前列腺癌细胞的辐射敏感性
5. Improving cryosurgical ablation of advanced stage prostate cancer through identification of molecular targets in a prostate cancer cell model. [D] . Klossner, Daniel Patrick. 2007

机译：通过鉴定前列腺癌细胞模型中的分子靶标来改善晚期前列腺癌的冷冻消融。
6. Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines [O] . Stephen Wilson, Jianfei Qi, Fabian V. Filipp -1

机译：精制基于ChIP-Seq的雄激素不敏感和雄激素反应性前列腺癌细胞系
7. Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer [O] . Kimberly L. Santucci, John M. Baust, Kristi K. Snyder, 2016

机译：细胞周期阶段对雄激素不敏感前列腺癌冷冻响应敏感性的影响研究
8. Cell Cycle Dependence of TRIAL Sensitivity in Prostate Cancer Cells; Annual rept. 24 Oct 2006-23 Oct 2007 [R] . McConkey, D. J. 2007

机译：细胞周期依赖于前列腺癌细胞的TRIaL敏感性;年度报告。 2006年10月24日至2007年10月23日

Investigation of the Impact of Cell Cycle Stage on Freeze Response Sensitivity of Androgen-Insensitive Prostate Cancer

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