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首页> 外文期刊>Technology in cancer research & treatment. >Stereotactic body radiation therapy: evaluation of setup accuracy and targeting methods for a new couch integrated immobilization system.
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Stereotactic body radiation therapy: evaluation of setup accuracy and targeting methods for a new couch integrated immobilization system.

机译：立体定向放射疗法：评估一种新型沙发集成固定系统的安装精度和靶向方法。

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A new stereotactic frame system was designed at Indiana University to utilize the precision motion control of newer accelerator couches and treat obese patients previously untreatable in other frame systems during stereotactic body radiation therapy (SBRT). The repositioning accuracy and target reproducibility of this frame was evaluated in the treatment of both lung and liver tumors. The external coordinate system on the new frame was validated using a phantom system. Translational motions were carried out using couch motors. Five patients were treated with SBRT and twenty-three verification CT scans were acquired. The displacement of the gross tumor volume (GTV) and adjacent vertebral body between the original CT scan and the verification CT scans was determined. The mean setup accuracy for the patient study was less than 5 mm. Mean displacement of the GTV was 3.0 mm (0.0-6.0 mm) in the lateral (x) direction, 4.1 mm (0.0-8.9 mm) in the superior-inferior (y) direction, and 2.6 mm (0.0-10.0 mm) in the cranio-caudal (z) direction. Comparison of vertebral body position showed mean displacement of 2.4 mm (0.0 to 8.0 mm), 1.9 mm (0.0 mm to 2.0 mm), and 0.9 mm (0.0 to 5.0 mm) for the same shift directions. Repositioning could be accurately carried out from an initial reference position using the treatment couch controllers. Adequate set-up accuracy using a frame system capable of accommodating wide girth patients was achieved and was comparable to other published studies for narrower frames. With these results, a 5 mm expansion for PTV margins remains the standard for our institution.
机译：印第安纳大学设计了一种新的立体定向框架系统，以利用较新的加速床的精确运动控制，并治疗在立体定向放射治疗（SBRT）期间以前无法在其他框架系统中治愈的肥胖患者。在肺和肝肿瘤的治疗中评估了该框架的重新定位精度和靶标可重复性。使用幻象系统验证了新框架上的外部坐标系。平移运动使用卧式电动机进行。 5例患者接受了SBRT治疗，获得了23例验证性CT扫描。确定了原始CT扫描和验证CT扫描之间的总肿瘤体积（GTV）和邻近椎体的位移。病人研究的平均安装精度小于5毫米。 GTV在横向（x）方向上的平均位移为3.0毫米（0.0-6.0毫米），在上下（y）方向上的平均位移为4.1毫米（0.0-8.9毫米），而在（x）方向上的平均位移为2.6毫米（0.0-10.0毫米）。颅尾（z）方向。椎体位置的比较显示，对于相同的移位方向，平均位移为2.4毫米（0.0到8.0毫米），1.9毫米（0.0毫米到2.0毫米）和0.9毫米（0.0到5.0毫米）。可以使用治疗床控制器从初始参考位置精确地进行重新定位。使用能够容纳宽围患者的镜架系统，可以达到足够的设置精度，并且与其他较窄镜架的研究相当。有了这些结果，PTV边距扩展5毫米仍然是我们机构的标准。

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