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首页> 外文期刊>Tenside Surfactants Detergents: Journal for Theory, Technology and Application of Surfactants >Feasibility of a Natural Surfactant as a Stabilizer for Cosmetics with Liposome-Encapsulated Plant Stem Cells: Pre-Formulation and Formulation Through Stability Studies
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Feasibility of a Natural Surfactant as a Stabilizer for Cosmetics with Liposome-Encapsulated Plant Stem Cells: Pre-Formulation and Formulation Through Stability Studies

机译：天然表面活性剂作为脂质体包裹的植物干细胞化妆品稳定剂的可行性：通过稳定性研究的预先配制和配制

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摘要

During the formulation of liposome-containing products different problems can occur and the selection of a suitable carrier remains the greatest challenge. To estimate feasibility of a novel alkyl polyglucoside surfactant (hydroxystearyl alcohol and hydroxystearyl glucoside) as an emulsifier for cosmetics with liposome-encapsulated plant stem cells, we performed a two-phase study. In the first, the pre-formulation phase, the emulsifier's critical micelle concentration (CMC) and liposome-encapsulated active-emulsifier interactions were determined. The second phase was carried out to develop and characterize a cosmetic emulsion suitable to serve as a carrier for liposomes. The investigated emulsifier, with the obtained CMC value of 0.0085 wt.%, could be classified as liposome-friendly and can be used to develop stable and aesthetically acceptable cosmetics or even prospective pharmaceutical liposome-containing emulsions.
机译：在配制含脂质体的产品期间，可能会出现不同的问题，而选择合适的载体仍然是最大的挑战。为了评估新型烷基聚葡糖苷表面活性剂（羟基硬脂醇和羟基硬脂基葡萄糖苷）作为具有脂质体包裹的植物干细胞的化妆品乳化剂的可行性，我们进行了两阶段研究。首先，在配制前阶段，确定乳化剂的临界胶束浓度（CMC）和脂质体包封的活性-乳化剂相互作用。进行第二阶段以开发和表征适合用作脂质体载体的化妆品乳液。获得的CMC值为0.0085 wt。％的被研究的乳化剂可归类为脂质体友好型，可用于开发稳定且在美学上可接受的化妆品，甚至可用于预期的含药物脂质体的乳液。

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