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首页> 外文期刊>The American Journal of Surgery >Outcomes of pancreatic debridement in acute pancreatitis: Analysis of the nationwide inpatient sample from 1998 to 2010
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Outcomes of pancreatic debridement in acute pancreatitis: Analysis of the nationwide inpatient sample from 1998 to 2010

机译:急性胰腺炎胰腺清创术的结果:1998年至2010年全国住院患者样本的分析

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摘要

Background The objective of this study was to perform a national review of patients with acute pancreatitis (AP) who undergo pancreatic debridement (PD) to evaluate for risk factors of in-hospital mortality. Methods The Nationwide Inpatient Sample was used to identify patients with AP who underwent PD between 1998 and 2010. Risk factors for in-hospital mortality were assessed with multivariate logistic regression. Results From 1998 to 2010, there were 585,978 nonelective admissions with AP, of which 1,783 (.3%) underwent PD. From 1998 to 2010, the incidence of PD decreased from.44% to.25% (P <.01) and PD in-hospital mortality decreased from 29.0% to 15% (P <.05). Of patients undergoing PD, independent factors associated with increased odds of mortality were increased age (odds ratio [OR] 1.04, confidence interval [CI] 1.03 to 1.05; P <.01), sepsis with organ failure (OR 1.76, CI 1.24 to 2.51; P <.01), peptic ulcer disease (OR 1.83, CI 1.02 to 3.30; P <.05), liver disease (OR 2.27, CI 1.36 to 3.78; P <.01), and renal insufficiency (OR 1.78, CI 1.14 to 2.78; P <.05). Conclusions The incidence and operative mortality of PD have decreased significantly over the last decade in the United States with higher odds of dying in patients who are older, with chronic liver, renal, or ulcer disease, and higher rates of sepsis with organ failure.
机译:背景技术这项研究的目的是对接受胰腺清创术(PD)的急性胰腺炎(AP)患者进行全国性评估,以评估院内死亡的危险因素。方法采用全国住院患者样本来鉴定1998年至2010年间接受PD的AP患者。采用多因素logistic回归分析评估住院死亡率的危险因素。结果1998年至2010年,AP共有585,978例非选修招生,其中1,783例(.3%)接受了PD。从1998年到2010年,PD的发生率从4​​4%下降到25%(P <.01),PD的院内死亡率从29.0%下降到15%(P <.05)。在接受PD的患者中,与死亡几率增加相关的独立因素是年龄增加(几率[OR] 1.04,置信区间[CI] 1.03至1.05; P <.01),败血症伴器官衰竭(OR 1.76,CI 1.24至2.51; P <.01),消化性溃疡疾病(OR 1.83,CI 1.02至3.30; P <.05),肝病(OR 2.27,CI 1.36至3.78; P <.01)和肾功能不全(OR 1.78, CI 1.14至2.78; P <.05)。结论在过去的十年中,PD的发生率和手术死亡率在美国显着降低,其中年龄更大,患有慢性肝,肾或溃疡病的患者死亡的几率更高,并且败血症伴器官衰竭的发生率更高。

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