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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Rethinking indicators of microbial drinking water quality for health studies in tropical developing countries: Case study in northern coastal Ecuador
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Rethinking indicators of microbial drinking water quality for health studies in tropical developing countries: Case study in northern coastal Ecuador

机译：对热带发展中国家健康研究中微生物饮用水质量指标的反思：厄瓜多尔北部沿海地区的案例研究

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To address the problem of the health impacts of unsafe drinking water, methods are needed to assess microbiologic contamination in water. However, indicators of water quality have provided mixed results. We evaluate five assays (three for Escherichia coli and one each for enterococci and somatic coliphage) of microbial contamination in villages in rural Ecuador that rely mostly on untreated drinking water. Only membrane filtration for E. coli using mI agar detected a significant association with household diarrheal disease outcome (odds ratio = 1.29, 95% confidence interval = 1.02-1.65 in household containers and odds ratio = 1.18, 95% confidence interval = 1.02-1.37) in source samples. Our analysis and other published research points to the need for further consideration of study design factors, such as sample size and variability in measurements, when using indicator organisms, especially when relating water quality exposure to health outcomes. Although indicator organisms are used extensively in health studies, we argue that their use requires a full understanding of their purposes and limitations.
机译：为了解决不安全饮用水对健康的影响问题，需要采取方法来评估水中的微生物污染。但是，水质指标却提供了不同的结果。我们评估了厄瓜多尔乡村中主要依靠未经处理的饮用水的五种微生物污染检测方法（三种检测方法分别为大肠杆菌，肠球菌和体细胞噬菌体检测三项）。只有使用mI琼脂进行大肠杆菌的膜过滤才发现与家庭腹泻疾病的结果有显着相关性（家用容器中的奇数比= 1.29，95％置信区间= 1.02-1.65，比值比= 1.18，95％置信区间= 1.02-1.37 ）中的示例。我们的分析和其他已发表的研究指出，使用指示剂生物时，尤其是将水质暴露与健康状况相关联时，需要进一步考虑研究设计因素，例如样本大小和测量变异性。尽管指示剂生物在健康研究中被广泛使用，但我们认为使用它们需要充分了解其目的和局限性。

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