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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case report: Halicephalobus gingivalis: A rare cause of fatal meningoencephalomyelitis in humans
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Case report: Halicephalobus gingivalis: A rare cause of fatal meningoencephalomyelitis in humans

机译：病例报告：牙龈无头孢子菌：人类致命性脑膜脑脊髓炎的罕见原因

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摘要

The genus Halicephalobus consists of eight species of free-living nematodes. Only one species (H. gingivalis) has been reported to infect vertebrates. Human infection is extremely rare, and only four cases have been reported in the literature. These nematodes seem to exhibit neurotropism, but their life cycle, mode of infection, and risk factors are poorly understood. Neurohelminthiases are not commonly recognized in the United States and when they do occur, pose great diagnostic challenges because of lack of appropriate non-invasive screening and/or confirmatory tests. We report a challenging case of meningoencephalomyelitis caused by a Halicephalobus sp., in which the patient had a rapidly deteriorating clinical course. The case did not raise any clinical suspicion of neurohelminthiases, although increased eosinophils were present in the cerebrospinal fluid. This case presents an opportunity to highlight the importance of considering parasitic infection in meningoencephalitis or meningoencephalomyelitis presenting atypically.
机译：Halicephalobus属由八种自由生活的线虫组成。据报道只有一种物种（牙龈嗜血杆菌）感染脊椎动物。人类感染极为罕见，文献中仅报道了四例。这些线虫似乎表现出神经嗜性，但对其生命周期，感染方式和危险因素了解甚少。神经蠕虫病在美国并不普遍被认可，当它们发生时，由于缺乏适当的非侵入性筛查和/或确认性测试而给诊断带来了巨大挑战。我们报告了由Halicephalobus sp。引起的脑膜脑脊髓炎的具有挑战性的案例，其中患者的临床病情迅速恶化。尽管脑脊髓液中存在嗜酸性粒细胞增多，但该病例并未引起对神经寄生虫病的任何临床怀疑。这种情况提供了一个机会，以突出考虑在非典型表现的脑膜脑炎或脑膜脑脊髓炎中考虑寄生虫感染的重要性。

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