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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Case report: Disseminated Mycobacterium tuberculosis infection in a dog
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Case report: Disseminated Mycobacterium tuberculosis infection in a dog

机译：病例报告：狗中的结核分枝杆菌感染

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An uncommon disseminated Mycobacterium tuberculosis infection is described in a 12-year-old female dog presenting with fever, dyspnea, cough, weight loss, lymphadenopathy, melena, epistaxis, and emesis. The dog had a history of close contact with its owner, who died of pulmonary tuberculosis. Radiographic examination revealed diffuse radio-opaque images in both lung lobes, diffuse visible masses in abdominal organs, and hilar and mesenteric lymphadenopathy. Bronchial washing samples and feces were negative for acid-fast organisms. Polymerase chain reaction (PCR)-based species identification of bronchial washing samples, feces, and urine revealed M. tuberculosis using PCR-restriction enzyme pattern analysis-PRA. Because of public health concerns, which were worsened by the physical condition of the dog, euthanasia of the animal was recommended. Rough and tough colonies suggestive of M. tuberculosis were observed after microbiological culture of lung, liver, spleen, heart, and lymph node fragments in L?wenstein-Jensen and Stonebrink media. The PRA analysis enabled diagnosis of M. tuberculosis strains isolated from organs.
机译：在一只12岁的母狗中发现一种罕见的弥散性结核分枝杆菌感染，表现为发烧，呼吸困难，咳嗽，体重减轻，淋巴结肿大，黑便，鼻epi和呕吐。这只狗与主人死于肺结核，有密切接触的历史。影像学检查发现两个肺叶均弥漫着不透射线的影像，腹部器官弥散可见可见肿块，肺门和肠系膜淋巴结肿大。支气管洗涤样品和粪便对耐酸生物体呈阴性。基于聚合酶链反应（PCR）的支气管清洗样品，粪便和尿液种类鉴定使用PCR限制性酶图谱分析-PRA揭示了结核分枝杆菌。由于公共健康问题，由于狗的身体状况而恶化，因此建议对动物实施安乐死。在L？wenstein-Jensen和Stonebrink培养基中进行肺，肝，脾，心脏和淋巴结碎片的微生物培养后，观察到表明结核分枝杆菌的粗糙和坚硬菌落。 PRA分析能够诊断从器官分离出的结核分枝杆菌菌株。

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