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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >High anti-cryptosporidium parvum igg seroprevalence in hiv-infected adults in limpopo, south africa
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High anti-cryptosporidium parvum igg seroprevalence in hiv-infected adults in limpopo, south africa

机译:南非林波波的艾滋病毒感染成年人中高抗隐孢子虫的igg血清阳性率

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A seroepidemiological study was performed to determine the seroprevalence of Cryptosporidium in human immunodeficiency virus (HIV)-infected adults and local university students in the Limpopo Province, South Africa. Using a custom anti-C. parvum immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA), the seroprevalence of Cryptosporidium was found to be significantly higher (75.3%; 146 of 193) in HIV-infected individuals compared with student volunteers (32.8%; 19 of 58) (P < 0.001). A more recent diagnosis of HIV was associated with anti-C. parvum IgG seropositivity, as was lower weight among HIV-infected women. This is the first seroepidemiologic study of Cryptosporidium in rural South Africa, and it shows high endemicity among the HIV-infected population. In addition to raising the possibility of significant Cryptosporidium-related morbidities, this finding reveals that in Limpopo and perhaps in other low-income, rural populations, interrupting waterborne pathogen transmission will require strategies effective against environmentally hardy parasites such as Cryptosporidium.
机译:进行了一项血清流行病学研究,以确定南非林波波省感染人类免疫缺陷病毒(HIV)的成年人和当地大学生中隐孢子虫的血清阳性率。使用自定义的反C。如果使用小球免疫球蛋白G(IgG)酶联免疫吸附试验(ELISA),发现感染HIV的个体中隐孢子虫的血清阳性率显着高于学生志愿者(32.8%; 58人中的19人)(75.3%; 193名中的146名) (P <0.001)。 HIV的最新诊断与抗C有关。 IgG血清反应阳性,HIV感染妇女体重较轻。这是南非农村地区隐孢子虫的首次血清流行病学研究,它显示了艾滋病毒感染人群中的高流行性。除了增加发生隐孢子虫相关疾病的可能性外,这一发现还表明,在林波波河以及其他低收入农村人口中,中断水生病原体的传播将需要有效地应对环境艰难的寄生虫(如隐孢子虫)的策略。

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