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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Cross-sectional study to assess risk factors for leishmaniasis in an endemic region in Sri Lanka
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Cross-sectional study to assess risk factors for leishmaniasis in an endemic region in Sri Lanka

机译：评估斯里兰卡流行区域利什曼病危险因素的横断面研究

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摘要

Sri Lanka reports significantly more cutaneous leishmaniasis (CL) cases than visceral leishmaniasis (VL) cases, both of which are caused by Leishmania donovani MON-37. A cross-sectional study conducted in an area with a high prevalence of CL prevalent included 954 participants of an estimated population of 61,674 to estimate the number of CL cases, ascertain whether there is a pool of asymptomatic VL cases, and identify risk factors for transmission. A total of 31 cases of CL were identified, of whom 21 were previously diagnosed and 10 were new cases. Using rK39 rapid diagnostic test to detect antibodies against Leishmania spp., we found that only one person was seropositive but did not have clinical symptoms of CL or VL, which indicated low transmission of VL in this area. c2 test, independent sample t-test, and multivariate analysis of sociodemographic and spatial distribution of environmental risk factors showed that living near paddy fields is associated with increased risk for transmission of CL (P ￡ 0.01).
机译：斯里兰卡报告的皮肤利什曼病（CL）病例明显多于内脏利什曼病（VL）病例，这两种情况都是由多形利什曼原虫MON-37引起的。在CL患病率高的地区进行的一项横断面研究包括954名估计人口为61,674人的参与者，以评估CL病例数，确定是否存在无症状VL病例库并确定传播的危险因素。共鉴定出31例CL，其中先前诊断为21例，新诊断为10例。使用rK39快速诊断测试检测抗利什曼原虫的抗体，我们发现只有一个人是血清反应阳性的，但没有CL或VL的临床症状，这表明VL在该区域的传播率较低。 c2检验，独立样本t检验以及环境风险因素的社会人口学和空间分布的多元分析表明，居住在稻田附近与CL传播的风险增加相关（P ￡ 0.01）。

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